Aims.For the past quarter of a century, Frank et al.’s (1991) consensus-based definitions of
major depressive disorder (MDD) episode, remission, recovery, relapse and recurrence have …

Informal care may substitute for formal long‐term care that is often publicly funded or subsidized.
The costs of informal caregiving are borne by the caregiver and may consist of worse …

Posttreatment high-grade gliomas are usually monitored with contrast-enhanced MRI, but
its diagnostic accuracy is limited as it cannot adequately distinguish between true tumor …

Background Infection-associated hemolytic uremic syndrome (IA-HUS), most often due to
infection with Shiga toxin-producing bacteria, mainly affects young children. It can be acutely …

Background: Post-treatment high-grade gliomas are usually monitored with contrast-enhanced
MRI, but its diagnostic accuracy is limited as it cannot adequately distinguish between …

Whether children incur different risks from xenobiotics than adults will depend on the
exposure, biokinetics, and dynamics of compound. In this paper, current knowledge on …

The urinary excretion of seven aldehydes, acetone, coproporphyrin III and 8-hydroxy-2′-deoxyguanosine
(8-OH-dG) as non-invasive biomarkers of oxidative damage was measured in …

Carbon tetrachloride (CCl 4 ) is a model compound for inducing free radical damage in liver.
In this study 10 biomarkers in rats treated ip with three different single doses of CCl 4 (0.25, …

… de standaardprocedure wordt de TDI afgeleid door de NOAEL te delen door
onzekerheidsfactoren (10 x 10) voor intra- en interspeciesverschillen. Het blijft hierbij echter de …

… /min, fentanyl is rapidly cleared from the central (blood) compartment after intravenous
administration and has a volume of distribution higher than 3 L/kg in humans. When the …