Exposure to 900 MHz electromagnetic fields activates the mkp-1/ERK pathway and causes blood-brain barrier damage and cognitive impairment in rats

…, L Yang, Q Chen, L Tan, S Zuo, H Feng, Z Chen… - Brain research, 2015 - Elsevier
With the rapid increase in the number of mobile phone users, the potential adverse effects
of the electromagnetic field radiation emitted by a mobile phone has become a serious …

Post-hemorrhagic hydrocephalus: recent advances and new therapeutic insights

Q Chen, Z Feng, Q Tan, J Guo, J Tang, L Tan… - Journal of the …, 2017 - Elsevier
Post-hemorrhagic hydrocephalus (PHH), also referred to as progressive ventricular
dilatation, is caused by disturbances in cerebrospinal fluid (CSF) flow or absorption following …

Intracerebral hematoma contributes to hydrocephalus after intraventricular hemorrhage via aggravating iron accumulation

Q Chen, J Tang, L Tan, J Guo, Y Tao, L Li, Y Chen… - Stroke, 2015 - Am Heart Assoc
Background and Purpose— The intraventricular hemorrhage (IVH) secondary to intracerebral
hemorrhage (ICH) was reported to be relevant to a higher incidence of hydrocephalus, …

Role of glibenclamide in brain injury after intracerebral hemorrhage

B Jiang, L Li, Q Chen, Y Tao, L Yang, B Zhang… - Translational stroke …, 2017 - Springer
Brain edema following intracerebral hemorrhage (ICH) causes severe secondary brain
injury, and no efficient pharmacological preventions are available. The present study was …

[PDF][PDF] REM sleep-active hypothalamic neurons may contribute to hippocampal social-memory consolidation

H Qin, L Fu, T Jian, W Jin, M Liang, J Li, Q Chen… - Neuron, 2022 - cell.com
The hippocampal CA2 region plays a key role in social memory. The encoding of such memory
involves afferent activity from the hypothalamic supramammillary nucleus (SuM) to CA2. …

Cannabinoid receptor-2 stimulation suppresses neuroinflammation by regulating microglial M1/M2 polarization through the cAMP/PKA pathway in an experimental …

…, Q Chen, J Zhang, Q Tan, H Feng, Z Chen… - Brain, behavior, and …, 2016 - Elsevier
Excessive inflammatory responses are involved in secondary brain injury during germinal
matrix hemorrhage (GMH). The process of microglial polarization to the pro-inflammatory M1 …

A cannabinoid receptor 2 agonist prevents thrombin-induced blood–brain barrier damage via the inhibition of microglial activation and matrix metalloproteinase …

…, J Tang, Q Chen, Y Yang, Z Feng, Y Chen… - Translational stroke …, 2015 - Springer
Thrombin mediates the life-threatening cerebral edema and blood–brain barrier (BBB) damage
that occurs after intracerebral hemorrhage (ICH). We previously found that the selective …

[HTML][HTML] Inflammatory regulation by driving microglial M2 polarization: neuroprotective effects of cannabinoid receptor-2 activation in intracerebral hemorrhage

…, F Zhou, N Yin, T Qiang, Z Haowen, C Qianwei… - Frontiers in …, 2017 - frontiersin.org
The cannabinoid receptor-2 (CB2R) was initially thought to be the “peripheral cannabinoid
receptor.” Recent studies, however, have documented CB2R expression in the brain in both …

Sonogashira cross-coupling of aryltrimethylammonium salts

Q Chen, F Gao, H Tang, M Yao, Q Zhao, Y Shi… - ACS …, 2019 - ACS Publications
A protocol for C(sp)–C(sp 2 ) bond formation via the Sonogashira coupling reaction involving
C–N bond cleavage with aryltrimethylammonium triflate as an electrophilic coupling …

Simvastatin accelerates hematoma resolution after intracerebral hemorrhage in a PPARγ-dependent manner

Y Wang, Q Chen, Q Tan, Z Feng, Z He, J Tang… - …, 2018 - Elsevier
To date, the neuroprotective effects of statins on intracerebral hemorrhage (ICH) are not
well established. This study explored the effect and potential mechanism of simvastatin …