[HTML][HTML] Investigating the AC079305/DUSP1 Axis as Oxidative Stress-Related Signatures and Immune Infiltration Characteristics in Ischemic Stroke

J Fan, S Cao, M Chen, Q Yao, X Zhang, S Du… - … Medicine and Cellular …, 2022 - hindawi.com
Background. Oxidative stress (OS) and immune inflammation play complex intersections in
the pathophysiology of ischemic stroke (IS). However, a competing endogenous RNA- (…

The anti-aging effect of erythropoietin via the ERK/Nrf2-ARE pathway in aging rats

H Wu, J Zhao, M Chen, H Wang, Q Yao, J Fan… - Journal of Molecular …, 2017 - Springer
Erythropoietin (EPO) has a neuroprotective effect and can resist aging, which most likely occur
through EPO increasing the activity of antioxidant enzymes and scavenging free radicals. …

[HTML][HTML] Identification of a ferroptosis-related gene pair biomarker with immune infiltration landscapes in ischemic stroke: a bioinformatics-based comprehensive study

J Fan, M Chen, S Cao, Q Yao, X Zhang, S Du, H Qu… - BMC genomics, 2022 - Springer
Background Ischemic stroke (IS) is a principal contributor to long-term disability in adults. A
new cell death mediated by iron is ferroptosis, characterized by lethal aggregation of lipid …

[HTML][HTML] The prediction of asymptomatic carotid atherosclerosis with electronic health records: a comparative study of six machine learning models

J Fan, M Chen, J Luo, S Yang, J Shi, Q Yao… - BMC medical informatics …, 2021 - Springer
Background Screening carotid B-mode ultrasonography is a frequently used method to detect
subjects with carotid atherosclerosis (CAS). Due to the asymptomatic progression of most …

[HTML][HTML] PD-1 rs2227982 polymorphism is associated with the decreased risk of breast cancer in Northwest Chinese women: a hospital-based observational study

…, TB Jin, XB Ma, XH Liu, M Wang, K Liu, P Xu, QL Yao… - Medicine, 2016 - journals.lww.com
Programmed death-1 (PD-1) is crucial in cancer and is well characterized as a negative T-cell
regulator that functions by delivering inhibitory signals. We aimed to evaluate the …

Dynorphin A (1–8) inhibits oxidative stress and apoptosis in MCAO rats, affording neuroprotection through NMDA receptor and κ-opioid receptor channels

M Chen, X Zhang, J Fan, H Sun, Q Yao, J Shi, H Qu… - Neuropeptides, 2021 - Elsevier
The contents of Dynorphin A(1–8) decreased gradually in ischemic cortices in rats and an
intracerebroventricular administration of synthetic Dynorphin A(1–8) reduced the volume of …

rhEPO enhances cellular anti-oxidant capacity to protect long-term cultured aging primary nerve cells

H Wang, J Fan, M Chen, Q Yao, Z Gao, G Zhang… - Journal of Molecular …, 2017 - Springer
Erythropoietin (EPO) may protect the nervous system of animals against aging damage,
making it a potential anti-aging drug for the nervous system. However, experimental evidence …

Using PCG-Arginine nanoparticle mediated intranasal delivery of dynorphin A (1–8) to improve neuroprotection in MCAO rats

…, M Wang, H Sun, X Zhang, J Shi, J Fan, Q Yao… - Journal of Drug Delivery …, 2022 - Elsevier
In our previous research, the contents of dynorphin A(1–8) decreased gradually in ischemic
cortices in rats after transient focal cerebral ischemia and an intracerebroventricular …

[HTML][HTML] Erythropoietin suppresses D-galactose-induced aging of rats via the PI3K/Akt/Nrf2-ARE pathway

H Wu, M Chen, P Yan, Q Yao, J Fan… - International Journal of …, 2018 - ncbi.nlm.nih.gov
EPO (erythropoietin) is a hormone-like substance with a putative role in hematopoietic
regulation. Current research suggests that it exerts a neuroprotective effect by enhancing the …

Correlation between microalbuminuria and atherosclerotic intracranial and extracranial arterial stenosis in patients with cerebral infarction

X Zhang, M Chen, Q Yao, N Zhang, J Fan, J Shi… - Journal of Clinical …, 2022 - Elsevier
Background and aims Microalbuminuria (MAU) reflects the generalized vascular endothelial
dysfunction. Whether MAU has correlation with atherosclerotic intracranial and extracranial …