Forkhead transcription factor FoxO3a has been reported to have ambiguous functions and
distinct mechanisms in various solid tumors, including glioblastoma (GBM). Although a …

Glioblastoma multiforme (GBM) is notoriously resistant to radiation, and consequently, new
radiosensitizers are urgently needed. MicroRNAs are a class of endogenous gene …

The c-Myc oncogene is amplified in many tumor types. It is an important regulator of cell
proliferation and has been linked to altered miRNA expression, suggesting that c-Myc-regulated …

Glioblastoma (GBM) is one of the most lethal forms of human cancer, and new clinical
biomarkers and therapeutic targets are urgently required. microRNAs (miRNAs) are small, non-…

Background Isocitrate dehydrogenase wild-type (WT) glioblastoma (GBM) accounts for 90%
of all GBMs, yet only 27% of isocitrate dehydrogenase WT-GBMs have p53 mutations. …

Cerebral venous sinus thrombosis (CVST) rarely induces cerebral hemorrhage, and CVST
with cerebral hemorrhage during early pregnancy is extremely rare. Upon literature review, …

Cerebral ischemic stroke has long been recognized as a prevalent and serious neurological
disease that was associated with high mortality and morbidity. However, the current …

Mutations in isocitrate dehydrogenase 1 (IDH1) are found in> 70% of secondary glioblastomas
and lower-grade gliomas (grades II-III). Among the numerous phenotypic differences …

Gliomas are the most common type of primary malignancy of the central nervous system.
The identification of mutations in the gene encoding isocitrate dehydrogenase‑1 (IDH1) …

Chordoid glioma is a rare low-grade tumor that originates almost exclusively in the anterior
part of the third ventricle. The diagnosis and treatment of the tumor remain controversial. In …