User profiles for Rustu Onur

rustu onur

Professor of Medical Pharmacology
Verified email at neu.edu.tr
Cited by 1274

Persistent defect in transmitter release and synapsin phosphorylation in cerebral cortex after transient moderate ischemic injury

H Bolay, Y Gürsoy-Özdemir, Y Sara, R Onur, A Can… - Stroke, 2002 - Am Heart Assoc
Background and Purpose— Synaptic transmission is highly vulnerable to metabolic
perturbations. However, the long-term consequences of transient metabolic perturbations on …

Structural and functional characterization of simvastatin-induced myotoxicity in different skeletal muscles

NS Ozek, IB Bal, Y Sara, R Onur, F Severcan - Biochimica et Biophysica …, 2014 - Elsevier
Background Statins are the most commonly used drugs for the treatment of hypercholesterolemia.
Their most frequent side effect is myotoxicity. To date, it remains unclear whether …

Comparative neurotoxic effects of root canal filling materials on rat sciatic nerve

A Serper, O Üçer, R Onur, I Etikan - Journal of Endodontics, 1998 - Elsevier
The neurotoxic effects of the root canal filling materials—Endomethasone, N2 Universal,
Traitement SPAD, Sealapex, and Calciobiotic Root Canal Sealer (CRCS)—were investigated …

Low dose simvastatin induces compositional, structural and dynamic changes in rat skeletal extensor digitorum longus muscle tissue

N Ozek Simsek, Y Sara, R Onur… - Bioscience reports, 2010 - portlandpress.com
Statins are commonly used drugs in the treatment of hypercholesterolaemia. There are
many adverse effects of statins on skeletal muscle, but the underlying mechanisms remain …

Effects of Cerebral Ischemia on N-Methyl-d-Aspartate and Dihydropyridine-Sensitive Calcium Currents: An Electrophysiological Study in the Rat Hippocampus In …

T Dalkara, C Ayata, M Demirci, G Erdemli, R Onur - Stroke, 1996 - Am Heart Assoc
Background and Purpose During cerebral ischemia, both promoting and limiting factors are
present for activation of the N-methyl-d-aspartate (NMDA) receptor ion channel and the …

Facilitatory effects of dexamethasone on neuromuscular transmission

T Dalkara, R Onur - Experimental neurology, 1987 - Elsevier
The beneficial effects of glucocorticoids in myasthenia gravis are attributed to their
immunosuppressive actions. There are also studies reporting direct facilitatory as well as depressant …

Glycine is required for NMDA receptor activation: electrophysiological evidence from intact rat hippocampus

T Dalkara, G Erdemli, S Barun, R Onur - Brain research, 1992 - Elsevier
Fimbrial/commissural stimulation evokes a prolonged negative field potential in stratum
radiatum of CA1 region of the rat hippocampus, in situ, upon activation of N-methyl-d-aspartate (…

Differential contractile impairment of fast-and slow-twitch skeletal muscles in a rat model of doxorubicin-induced congestive heart failure

M Ertunc, Y Sara, R Onur - Pharmacology, 2009 - karger.com
Congestive heart failure (CHF) is associated with exercise intolerance that cannot be entirely
explained by hypoperfusion of the skeletal muscles. We studied the contractile properties …

Contractility and electrophysiological parameters of cremaster muscles of boys with a hernia or undescended testis

M Bingöl-Koloğlu, Y Sara, FC Tanyel, R Onur… - Journal of pediatric …, 1998 - Elsevier
Background/Purpose: The cremaster muscle (CM) has been considered to participate in
regulation of blood flow and temperature of the testis. Its contribution to testicular descent has …

Mechanisms involved in contractile differences among cremaster muscles according to localization of testis

…, M Ertunç, N Büyükpamukçu, R Onur - Journal of pediatric surgery, 2001 - Elsevier
Background/Purpose: Evidence suggests differences in contractility in cremaster muscles (CM)
associated with undescended testis caused by alterations of autonomic innervation. …