Functional limitations for the vitamin K cycle, caused either by mutations in gamma-glutamyl
carboxylase or vitamin K epoxide reductase genes, result in hereditary deficiency of vitamin …

Background Cavernous malformations (CMs) of the central nervous system (CNS) are
angiographically occult vascular lesions that affect approximately 0.5 % of the general population, …

Brain metastases are a challenging manifestation of renal cell carcinoma. We have a limited
understanding of brain metastasis tumor and immune biology, drivers of resistance to …

Objective: Graph theory applications are commonly used in connectomics research to better
understand connectivity architecture and characterize its role in cognition, behavior and …

Topiramate (TPM) is a widely used antiepileptic and antimigraine agent which has been
shown to exert neuroprotective effects in various experimental traumatic brain injury and stroke …

BACKGROUND Human cadavers are an essential component of anatomy education.
However, access to cadaveric specimens and laboratory facilities is limited in most parts of the …

Background: Advances in computer sciences, including novel 3-dimensional rendering
techniques, have enabled the creation of cloud-based virtual reality (VR) interfaces, making real-…

OBJECTIVE In daily practice, neurosurgeons face increasing numbers of patients using aspirin
(acetylsalicylic acid, ASA). While many of these patients discontinue ASA 7–10 days prior …

Objective. Deep brain stimulation (DBS) surgery has increasingly been performed for the
treatment of movement disorders and is associated with a wide array of complications. We …

BACKGROUND: An understanding of the anatomy of white matter tracts and their 3-dimensional
(3D) relationship with each other is important for neurosurgical practice. The fiber …