[HTML][HTML] Undifferentiated headache: broadening the approach to headache in children and adolescents, with supporting evidence from a nationwide school-based …

…, TS Aslan, U Uygunoglu, A Tüfekçi, SI Alp… - The journal of headache …, 2018 - Springer
Background Headache is a leading disabler in adults worldwide. In children and adolescents,
the same may be true but the evidence is much poorer. It is notable that published …

Use of the International Classification of Headache Disorders, criteria in the diagnosis of primary headache in schoolchildren: epidemiology study from eastern Turkey

R Alp, SI Alp, Y Palanci, H Sur, UT Boru… - …, 2010 - journals.sagepub.com
We aimed to determine the prevalence of primary headache among schoolchildren in the
city of Agri, located in eastern Turkey, where geographical, climatic and socio-economic …

Design, synthesis and docking studies of benzimidazole derivatives as potential EGFR inhibitors

…, B Guven, Z Kara, AS Gurkan-Alp… - European journal of …, 2019 - Elsevier
In this study, a series of benzimidazoles bearing thiosemicarbazide chain or triazole and
thiadiazole rings were designed and synthesized. Crystal and molecular structure of the …

[PDF][PDF] The Prevalence of Multiple Sclerosis in the North Caucasus Region of Turkey: Door-to-Door Epidemiological Field Study.

R Alp, S İLHAN ALP, Y Planci, Z Yapici… - Archives of …, 2012 - academia.edu
Background: The prevalence rate of multiple sclerosis (MS) might differ between countries
depending on whether the data is obtained from hospital-based or population-based studies. …

Synthesis, anticancer activities and molecular modeling studies of novel indole retinoid derivatives

AS Gurkan-Alp, M Mumcuoglu, CA Andac… - European journal of …, 2012 - Elsevier
In this study, novel (E)-3-(5-substituted-1H-indol-3-yl)-1-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)prop-2-en-1-one
(5(a–e)) derivatives were synthesized and their …

Synthesis and biological evaluation of a series of dithiocarbamates as new cholinesterase inhibitors

MD Altıntop, AS Gurkan‐Alp, Y Özkay… - Archiv der …, 2013 - Wiley Online Library
In the present paper, a novel series of dithiocarbamates was synthesized via the treatment
of 4‐(trifluoromethyl)benzyl chloride with appropriate sodium salts of N,N‐disubstituted …

Nilotinib exhibits less toxicity than imatinib and influences the immune state by modulating iNOS, p-p38 and p-JNK in LPS/IFN gamma-activated macrophages

…, T Ozkan, A Koc, Y Hekmatshoar, AS Gurkan-Alp… - Toxicology in Vitro, 2024 - Elsevier
In this study, we aimed to analyze the effects of first and second-generation Bcr-Abl tyrosine
kinase inhibitors, imatinib and nilotinib on LPS/IFN gamma activated RAW 264.7 …

Synthesis of some benzimidazole-derived molecules and their effects on PARP-1 activity and MDA-MB-231, MDA-MB-436, MDA-MB-468 breast cancer cell viability

AS Gurkan-Alp, M Alp, AZ Karabay… - Anti-Cancer Agents …, 2020 - ingentaconnect.com
Background: Poly (ADP-ribosyl) polymerase-1 (PARP-1) inhibitors are compounds that are
used to treat cancers, which are defective in DNA-repair and DNA Damage-Response (DDR) …

Cavernous hemangioma: a rare cause for secondary parkinsonism: a case report

R Alp, Sİ Alp, H Üre - International Journal of Neuroscience, 2009 - Taylor & Francis
A 72-year-old female was admitted to our outpatient clinic with the complaints of slowed
movements and sudden speeding up of her walk. She was identified to have cavernous …

Quality of sleep and insomny violence in university students in the period of COVID-19.

Alp, M Deveci, B Erdal, RB Akalın, D Terzi - 2020 - cabidigitallibrary.org
Aim: To determine the sleep quality and insomnia severity of university students and the
factors affecting them during the coronavirus pandemic (COVID-19) process. Materials and …