User profiles for Shanmugakonar Muralitharan
Muralitharan ShanmugakonarLaboratory Manager, Laboratory Animal Research Centre, Qatar University Verified email at qu.edu.qa Cited by 1130 |
[HTML][HTML] Tight junction proteins and signaling pathways in cancer and inflammation: a functional crosstalk
The ability of epithelial cells to organize through cell–cell adhesion into a functioning
epithelium serves the purpose of a tight epithelial protective barrier. Contacts between adjacent …
epithelium serves the purpose of a tight epithelial protective barrier. Contacts between adjacent …
RAS-mediated oncogenic signaling pathways in human malignancies
Abnormally activated RAS proteins are the main oncogenic driver that governs the
functioning of major signaling pathways involved in the initiation and development of human …
functioning of major signaling pathways involved in the initiation and development of human …
[HTML][HTML] Claudin-1, a double-edged sword in cancer
…, SK Yadav, R Krishnankutty, S Muralitharan… - International journal of …, 2020 - mdpi.com
Claudins, a group of membrane proteins involved in the formation of tight junctions, are
mainly found in endothelial or epithelial cells. These proteins have attracted much attention in …
mainly found in endothelial or epithelial cells. These proteins have attracted much attention in …
[HTML][HTML] Chronic cadmium exposure alters cardiac matrix metalloproteinases in the heart of Sprague-Dawley rat
The aim of this study was to evaluate the role of chronic cadmium exposure in modulating
cardiac matrix metalloproteinases (MMPs) in the heart of rats. Adult male Sprague-Dawley rats …
cardiac matrix metalloproteinases (MMPs) in the heart of rats. Adult male Sprague-Dawley rats …
[HTML][HTML] Cadmium: An emerging role in adipose tissue dysfunction
Cadmium (Cd) is a toxic heavy metal that is widespread in the environment due to the substantial
anthropogenic inputs from the agriculture and industrial sectors. The toxic impact of Cd …
anthropogenic inputs from the agriculture and industrial sectors. The toxic impact of Cd …
Absence of deafness‐associated connexin‐26 (GJB2) gene mutations in the Omani population
…, N Al‐Wardy, A Al‐Khayat, M Shanmugakonar… - Human …, 2001 - Wiley Online Library
We have investigated the prevalence of mutations in the connexin 26 (GJB2) gene in Omani
population using both PCR‐RFLP and direct DNA sequencing methods. Two common …
population using both PCR‐RFLP and direct DNA sequencing methods. Two common …
[HTML][HTML] NF-κB essential modulator (NEMO) is critical for thyroid function
…, M Zannini, T de Cristofaro, M Shanmugakonar… - Journal of Biological …, 2016 - ASBMB
The I-κB kinase (IKK) subunit NEMO/IKKγ (NEMO) is an adapter molecule that is critical for
canonical activation of NF-κB, a pleiotropic transcription factor controlling immunity, …
canonical activation of NF-κB, a pleiotropic transcription factor controlling immunity, …
Identification of prognosis markers in pediatric high-risk acute lymphoblastic leukemia
…, R Al-Mjeni, C Li, S Muralitharan… - Pediatric hematology …, 2005 - Taylor & Francis
Gene expression profiling may improve the understanding of the biology behind relapse in
pediatric acute lymphoblastic leukemia. Using suppression subtractive hybridization (SSH), …
pediatric acute lymphoblastic leukemia. Using suppression subtractive hybridization (SSH), …
Myofibrillogenesis regulator 1 gene (MR-1) mutation in an Omani family with paroxysmal nonkinesigenic dyskinesia
A Hempelmann, S Kumar, S Muralitharan, T Sander - Neuroscience letters, 2006 - Elsevier
Two recurrent missense mutations (c.20C>T: A7V; c.26C>T: A9V) in the gene encoding the
myofibrillogenesis regulator 1 (MR-1) have been shown to cause autosomal dominant …
myofibrillogenesis regulator 1 (MR-1) have been shown to cause autosomal dominant …
Novel spectrum of perforin gene mutations in familial hemophagocytic lymphohistiocytosis in ethnic Omani patients
S Muralitharan, YA Wali, D Dennison… - American journal of …, 2007 - Wiley Online Library
Familial hemophagocytic lymphohistiocytosis (FHL) is an autosomal recessive immune
disorder, characterized by fever, hepatosplenomegaly, pancytopenia, hypertriglyceridemia, …
disorder, characterized by fever, hepatosplenomegaly, pancytopenia, hypertriglyceridemia, …