User profiles for Shazia Bano

Shazia bano

Harvard University
Verified email at mgh.harvard.edu
Cited by 611

Impacting Pancreatic Cancer Therapy in Heterotypic in Vitro Organoids and in Vivo Tumors with Specificity-Tuned, NIR-Activable Photoimmunonanoconjugates …

G Obaid, S Bano, S Mallidi, M Broekgaarden… - Nano …, 2019 - ACS Publications
Despite untiring efforts to develop therapies for pancreatic ductal adenocarcinoma (PDAC),
survival statistics remain dismal, necessitating distinct approaches. Photodynamic priming (…

A combination of visudyne and a lipid‐anchored liposomal formulation of benzoporphyrin derivative enhances photodynamic therapy efficacy in a 3D model for …

…, G Obaid, MK Ruhi, K Moore, S Bano… - Photochemistry and …, 2019 - Wiley Online Library
A major objective in developing new treatment approaches for lethal tumors is to reduce
toxicity to normal tissues while maintaining therapeutic efficacy. Photodynamic therapy ( PDT ) …

Photodynamic therapy, priming and optical imaging: Potential co-conspirators in treatment design and optimization—a Thomas Dougherty Award for Excellence in …

P De Silva, MA Saad, HC Thomsen, S Bano… - Journal of Porphyrins …, 2020 - World Scientific
Photodynamic therapy is a photochemistry-based approach, approved for the treatment of
several malignant and non-malignant pathologies. It relies on the use of a non-toxic, light …

Remediating desmoplasia with EGFR‐targeted photoactivable multi‐inhibitor liposomes doubles overall survival in pancreatic cancer

G Obaid, S Bano, H Thomsen, S Callaghan… - Advanced …, 2022 - Wiley Online Library
Desmoplasia is characteristic of pancreatic ductal adenocarcinoma (PDAC), which exhibits
5‐year survival rates of 3%. Desmoplasia presents physical and biochemical barriers that …

Photodynamic therapy: Promoting in vitro efficacy of photodynamic therapy by liposomal formulations of a photosensitizing agent

I Rizvi, G Obaid, S Bano, T Hasan… - Lasers in surgery and …, 2018 - Wiley Online Library
Objective A relatively low level of lysosomal photodamage has been shown capable of
promoting the efficacy of photodamage simultaneously or subsequently directed to mitochondrial/…

Nanolipid formulations of benzoporphyrin derivative: exploring the dependence of nanoconstruct photophysics and photochemistry on their therapeutic index in …

G Obaid, W Jin, S Bano, D Kessel… - Photochemistry and …, 2019 - Wiley Online Library
With the rapidly emerging designs and applications of light‐activated, photodynamic therapy
( PDT )‐based nanoconstructs, photonanomedicines ( PNM s), an unmet need exists to …

[PDF][PDF] Callus induction and regeneration in seed explants of rice (Oryza sativa cv. Swat-II

S Bano, M Jabeen, F Rahim, I Ilahi - Pakistan Journal of Botany, 2005 - pakbs.org
Seeds of rice (Oryza sativa cv. Swat-II) were inoculated onto MS medium containing various
concentrations of auxins and cytokinins. Excellent callus resulted on MS containing 2, 4-D …

Microwave-assisted green synthesis of superparamagnetic nanoparticles using fruit peel extracts: surface engineering, T2 relaxometry, and photodynamic treatment …

S Bano, S Nazir, A Nazir, S Munir… - International Journal …, 2016 - Taylor & Francis
Superparamagnetic iron oxide nanoparticles (SPIONs) have the potential to be used as
multimodal imaging and cancer therapy agents due to their excellent magnetism and ability to …

[HTML][HTML] NIR photodynamic destruction of PDAC and HNSCC nodules using triple-receptor-targeted photoimmuno-nanoconjugates: targeting heterogeneity in cancer

S Bano, G Obaid, JWR Swain, M Yamada… - Journal of clinical …, 2020 - mdpi.com
Receptor heterogeneity in cancer is a major limitation of molecular targeting for cancer
therapeutics. Single-receptor-targeted treatment exerts selection pressures that result in …

Paclitaxel loaded magnetic nanocomposites with folate modified chitosan/carboxymethyl surface; a vehicle for imaging and targeted drug delivery

S Bano, M Afzal, MM Waraich, K Alamgir… - International journal of …, 2016 - Elsevier
In this study, Paclitaxel (PTX) containing, bovine serum albumin (BSA) nanoparticles were
fabricated via a simple approach. Folic acid (FA) was conjugated to chitosan (CS)/…