We sought to determine whether mice deficient in the proinflammatory caspase-1, which
cleaves precursors of IL-1β and IL-18, were protected against ischemic acute renal failure (ARF)…

Background. Chronic kidney disease (CKD) is a growing health problem worldwide that leads
to end-stage kidney failure and cardiovascular complications. We aimed to determine the …

ABSTRACT. This study sought to investigate the cardiac and renal effects of rigorous versus
standard BP control on autosomal-dominant polycystic kidney disease (ADPKD). A …

Cardiovascular problems are a major cause of morbidity and mortality in patients with
autosomal-dominant polycystic kidney disease (ADPKD). Hypertension is a common early …

Autosomal-dominant polycystic kidney disease (ADPKD) is a systemic hereditary disorder
characterized by renal and extrarenal involvement with cystic and noncystic manifestations (1)…

Results Patients very much or extremely bothered by itching declined from 28% in 1996 to
18% in 2015. In 2012–2015, among patients nearly always or always bothered by itching, …

… Author links open overlay panel Mladen Knotek , Boris Rogachev , Wei Wang , Tevfik Ecder
, Vyacheslav Melnikov , Patricia E. Gengaro , Matthew Esson , Charles L. Edelstein , Charles …

Objective: According to the World Health Organization (WHO), anemia is the most common
disease, affecting> 1.5 billion people worldwide. Furthermore, iron deficiency anemia (IDA) …

… McSweeney , Didem Korular , Tevfik Ecder , Aicha Merouani , Jeremy Taylor , Vicki Slat-Vasquez
, Elizabeth J. Shpall , Roy B. Jones , Scott I. …

Vascular access remains one of the most challenging aspects of renal replacement therapy.
If the vascular access does not function properly, then haemodialysis will not remove …