User profiles for Thomas M. Bosley

Thomas M. Bosley, MD

Knights Templar Eye Foundation Professor of Ophthalmology and Neurology, Johns …
Verified email at jhmi.edu
Cited by 10923

Age‐related changes in peripheral and central nerve conduction in man

LJ Dorfman, TM Bosley - Neurology, 1979 - AAN Enterprises
Somatosensory evoked potential (SEP) latencies, motor and sensory nerve conduction
velocities (CVs), and F-wave latenies were measured in 15 elderly normal subjects (mean age …

Mutations in a Human ROBO Gene Disrupt Hindbrain Axon Pathway Crossing and Morphogenesis

JC Jen, WM Chan, TM Bosley, J Wan, JR Carr, U Rüb… - Science, 2004 - science.org
The mechanisms controlling axon guidance are of fundamental importance in understanding
brain development. Growing corticospinal and somatosensory axons cross the midline in …

[HTML][HTML] Mitochondrial abnormalities in patients with primary open-angle glaucoma

…, J Morales, TM Bosley - … ophthalmology & visual …, 2006 - arvojournals.org
purpose. Primary open-angle glaucoma (POAG) is the second most common cause of
blindness. It has been linked to mutations in the myocilin (MYOC) and optineurin (OPTN) genes, …

Homozygous HOXA1 mutations disrupt human brainstem, inner ear, cardiovascular and cognitive development

MA Tischfield, TM Bosley, MAM Salih, IA Alorainy… - Nature …, 2005 - nature.com
We identified homozygous truncating mutations in HOXA1 in three genetically isolated human
populations. The resulting phenotype includes horizontal gaze abnormalities, deafness, …

Homozygous mutations in ARIX (PHOX2A) result in congenital fibrosis of the extraocular muscles type 2

…, AH Awad, J Zwaan, PB Mullaney, TM Bosley… - Nature …, 2001 - nature.com
Isolated strabismus affects 1–5% of the general population 1. Most forms of strabismus are
multifactorial in origin; although there is probably an inherited component, the genetics of …

MR imaging of Tolosa-Hunt syndrome.

…, RC Sergott, PJ Savino, TM Bosley - American journal …, 1989 - Am Soc Neuroradiology
The Tolosa-Hunt syndrome consists of painful ophthalmoplegia caused by cavernous sinus
inflammation, which is responsive to steroid therapy. The MR features of 11 patients with the …

Modified optic nerve sheath decompression provides long-term visual improvement for pseudotumor cerebri

RC Sergott, PJ Savino, TM Bosley - Archives of ophthalmology, 1988 - jamanetwork.com
• Twenty-three patients with chronic papilledema associated with pseudotumor cerebri
underwent "modified" optic nerve sheath decompression for treatment of visual acuity and visual …

Carotid cavernous fistula: ophthalmological implications

…, SM Elkhamry, W Al-Rashed, TM Bosley - Middle East African …, 2009 - journals.lww.com
Carotid cavernous fistula (CCF) is an abnormal communication between the cavernous
sinus and the carotid arterial system. A CCF can be due to a direct connection between the …

Neurologic features of horizontal gaze palsy and progressive scoliosis with mutations in ROBO3

TM Bosley, MAM Salih, JC Jen, DDM Lin, D Oystreck… - Neurology, 2005 - AAN Enterprises
Objective: To review the neurologic, neuroradiologic, and electrophysiologic features of
autosomal recessive horizontal gaze palsy and progressive scoliosis (HGPPS), a syndrome …

Eurasian and African mitochondrial DNA influences in the Saudi Arabian population

…, AM González, JM Larruga, TM Bosley… - BMC evolutionary …, 2007 - Springer
Background Genetic studies of the Arabian Peninsula are scarce even though the region
was the center of ancient trade routes and empires and may have been the southern corridor …