Protective effects of erythropoietin against ethanol-induced apoptotic neurodegenaration and oxidative stress in the developing C57BL/6 mouse brain

…, S Gonenc, K Genc, S Genc, U Sonmez… - Developmental brain …, 2005 - Elsevier
The developing central nervous system is extremely sensitive to ethanol, with well-defined
temporal periods of vulnerability. Recent studies have shown that administration of ethanol to …

Protective effect of melatonin against head trauma-induced hippocampal damage and spatial memory deficits in immature rats

…, K Tugyan, N Uysal, U Sonmez, A Sonmez… - Neuroscience …, 2005 - Elsevier
It is well known that head trauma induces the cognitive dysfunction resulted from hippocampal
damage. In the present study, we aimed to demonstrate the effect of melatonin on …

Neuroprotective effects of resveratrol against traumatic brain injury in immature rats

Ü Sönmez, A Sönmez, G Erbil, I Tekmen, B Baykara - Neuroscience letters, 2007 - Elsevier
Childhood trauma resulting in traumatic brain injury (TBI) due to accidents and abuse is the
major cause of death and dysfunction in the young. Since there are no approved specific …

Neuroprotective effect of the peptides ADNF-9 and NAP on hypoxic–ischemic brain injury in neonatal rats

A Kumral, DC Yesilirmak, U Sonmez, H Baskin… - Brain research, 2006 - Elsevier
Perinatal asphyxia is an important cause of neonatal mortality and subsequent serious
sequelae such as motor and cognitive deficits and seizures. Recent studies have demonstrated …

Methamphetamine induces oligodendroglial cell death in vitro

…, U Sonmez, O Yilmaz, K Tugyan, B Ergur, A Sonmez… - Brain research, 2003 - Elsevier
We investigated whether the psychostimulant methamphetamine (METH) has a cytotoxic effect
on oligodendrocytes and which cell-death pathways are involved in the cytotoxic process. …

Protective effect of melatonin against maternal deprivation-induced acute hippocampal damage in infant rats

…, U Sonmez, C Pekcetin, G Erbil, A Sonmez - Neuroscience …, 2006 - Elsevier
It is known that maternal deprivation induces hippocampal damage in the developing brains.
In the present study, we examined the effects of melatonin on maternal deprivation-induced …

Neuroprotective effects of selenium and ginkgo biloba extract (EGb761) against ischemia and reperfusion injury in rat brain

G Erbil, S Ozbal, U Sonmez, C Pekcetin, K Tugyan… - Neurosciences …, 2008 - nsj.org.sa
OBJECTIVE: To determine the neuroprotective effects of Ginkgo biloba extract (EGb761) and
Selenium (Se), and the combination of these agents on ischemia/reperfusion (I/R) injury in …

Deoxycholate hydrogels of betamethasone-17-valerate intended for topical use: in vitro and in vivo evaluation

T Şenyiğit, I Tekmen, Ü Sönmez, P Santi… - International journal of …, 2011 - Elsevier
The aim of this study was to evaluate the suitability of sodium-deoxycholate (Na-DOC) gels
containing betamethasone-17-valerate (BMV) for topical application. The gels were …

Effects of lipoic acid in an experimentally induced hypertensive and diabetic rat model

…, K Tuğyan, C Pekcetin, U Sonmez… - Clinical and …, 2013 - Taylor & Francis
In this study, experimental diabetes and nephrectomy have been applied separately and
together in order to investigate the possible therapeutic effects of lipoic acid (LA) on …

Erythropoietin attenuates neuronal injury and potentiates the expression of pCREB in anterior horn after transient spinal cord ischemia in rats

A Sönmez, B Kabakçı, E Vardar, D Gürel, Ü Sönmez… - Surgical neurology, 2007 - Elsevier
BACKGROUND: Recent studies have suggested that EPO activates the CREB transcription
pathway and increases BDNF expression and production, which contributes to EPO-…