[HTML][HTML] miRNAs: biological and clinical determinants in epilepsy
WA Alsharafi, B Xiao, MM Abuhamed… - Frontiers in molecular …, 2015 - frontiersin.org
Recently, microRNAs (miRNAs) are reported to be crucial modulators in the pathogenesis
and potential treatment of epilepsies. To date, several miRNAs have been demonstrated to be …
and potential treatment of epilepsies. To date, several miRNAs have been demonstrated to be …
Micro RNA‐139‐5p negatively regulates NR 2A‐containing NMDA receptor in the rat pilocarpine model and patients with temporal lobe epilepsy
WA Alsharafi, B Xiao, J Li - Epilepsia, 2016 - Wiley Online Library
Objectives Regulation of N‐methyl‐d‐aspartate ( NMDA ) subunits NR 2A and NR 2B
expression during status epilepticus ( SE ) remains incompletely understood. Here we explored …
expression during status epilepticus ( SE ) remains incompletely understood. Here we explored …
Correlation between IL-10 and microRNA-187 expression in epileptic rat hippocampus and patients with temporal lobe epilepsy
WA Alsharafi, B Xiao, MM Abuhamed, FF Bi… - Frontiers in Cellular …, 2015 - frontiersin.org
Accumulating evidence is emerging that microRNAs (miRNAs) are key regulators in controlling
neuroinflammatory responses that are known to play a potential role in the pathogenesis …
neuroinflammatory responses that are known to play a potential role in the pathogenesis …
MicroRNA in glutamate receptor-dependent neurological diseases
WA Alsharafi, Z Luo, X Long, Y Xie, B Xiao - Clinical Science, 2017 - portlandpress.com
Glutamate-mediated excitotoxicity is the major neuropathological process contributing to
numerous neurological diseases. Recently, emerging evidence indicates that microRNAs (…
numerous neurological diseases. Recently, emerging evidence indicates that microRNAs (…
Effect of Khat on apoptosis and related gene Smac/DIABLO expression in the cerebral cortex of rats following transient focal ischemia
WA Alsharafi, F Bi, Y Hu, HM Mujlli, B Xiao - Environmental toxicology and …, 2015 - Elsevier
Background The leaves of the Khat shrub contain the major alkaloid compounds (cathinone)
and cathine. These compounds can induce apoptosis and exacerbate the acute cerebral …
and cathine. These compounds can induce apoptosis and exacerbate the acute cerebral …
Dynamic expression of microRNAs (183, 135a, 125b, 128, 30c and 27a) in the rat pilocarpine model and temporal lobe epilepsy patients
W Alsharafi, B Xiao - … (Formerly Current Drug Targets-CNS & …, 2015 - ingentaconnect.com
Recently, microRNAs (miRNAs) are emerging as new regulators in the pathogenesis of
temporal lobe epilepsy (TLE) and playing a major role in the inflammatory and immune …
temporal lobe epilepsy (TLE) and playing a major role in the inflammatory and immune …
Changes in the numbers and distribution of calretinin in the epileptic rat hippocampus
MM Abuhamed, X Bo, WA Alsharafi, L Jing… - Neurosciences …, 2010 - nsj.org.sa
OBJECTIVE: To examine calretinin (CR)-containing interneurons that degenerate in the
hippocampus in post status epilepticus (SE) rats at different time points. METHODS: This study …
hippocampus in post status epilepticus (SE) rats at different time points. METHODS: This study …
A detector generating algorithm for intrusion detection inspired by artificial immune system
WM Alsharafi, MN Omar - ARPN Journal of Engineering and …, 2015 - repo.uum.edu.my
Artificial immune system (AIS) allows us to inspire several ideas for the design of computer
intrusion detection.The standard of negative selection algorithm (NSA), offered by Stephanie …
intrusion detection.The standard of negative selection algorithm (NSA), offered by Stephanie …
Normal Profile Updating Method for Enhanced Packet Header Anomaly Detection
WM Alsharafi, MN Omar, NA Al-Majmar… - Emerging Trends in …, 2020 - Springer
There is a significant need for various Intrusion Detection Systems (IDS) methods for packet
behavior anomaly detection, due to the consistent exposure of packets to frequent intrusion …
behavior anomaly detection, due to the consistent exposure of packets to frequent intrusion …
[PDF][PDF] A Normal Profile Updating Method for False Positives Reduction in Anomaly Detection Systems
WM Alsharafi, MN Omar - academia.edu
The contribution of this paper is to investigate whether there is a possibility of further processing
of both the normal and abnormal data identified by any anomaly detector with the intent …
of both the normal and abnormal data identified by any anomaly detector with the intent …