[HTML][HTML] HTLV-1 tax functions as a ubiquitin E3 ligase for direct IKK activation via synthesis of mixed-linkage polyubiquitin chains
The HTLV-1 oncoprotein Tax plays a key role in CD4 + T cell transformation by promoting
cell proliferation and survival, mainly through permanent activation of the NK-κB pathway and …
cell proliferation and survival, mainly through permanent activation of the NK-κB pathway and …
[HTML][HTML] Digital cell atlas of mouse uterus: from regenerative stage to maturational stage
L Zhang, W Long, W Xu, X Chen, X Zhao, B Wu - Frontiers in Genetics, 2022 - frontiersin.org
Endometrium undergoes repeated repair and regeneration during the menstrual cycle.
Previous attempts using gene expression data to define the menstrual cycle failed to come to an …
Previous attempts using gene expression data to define the menstrual cycle failed to come to an …
[HTML][HTML] Validation of the Chinese version of the questionnaire for impulsive-compulsive disorders in Parkinson's disease
T Xu, L Cao, W Long, G Zhao - Frontiers in Neurology, 2021 - frontiersin.org
Background: Impulse control and related disorders (ICRDs) have gained recognition as a
severe complication of Parkinson's disease (PD) and are connected to poor quality of life and …
severe complication of Parkinson's disease (PD) and are connected to poor quality of life and …
[HTML][HTML] Ischemic stroke in a patient with Fahr's disease carrying biallelic mutations in the MYORG gene
Y Li, W Fang, W Long, G Zhao - Neurosciences Journal, 2022 - nsj.org.sa
Fahr’s disease (FD) is a neurodegenerative disorder characterized by symmetric calcifications
in the bilateral basal ganglia and dentate nuclei. Mutations in six genes are known to …
in the bilateral basal ganglia and dentate nuclei. Mutations in six genes are known to …
Hesperetin inhibits KSHV reactivation and is reversed by HIF1α overexpression
W Long, G Zhao, Y Wu - Journal of General Virology, 2021 - microbiologyresearch.org
Kaposi’s sarcoma-associated herpesvirus (KSHV), an oncogenic virus, has two life cycle
modes: the latent and lytic phases. KSHV lytic reactivation is important for both viral …
modes: the latent and lytic phases. KSHV lytic reactivation is important for both viral …
Multiagent bidirectionally-coordinated nets: Emergence of human-level coordination in learning to play starcraft combat games
… Although limited to toy examples in the beginning, reinforcement learning, as a means, has
long been applied to multiagent systems in order to learn optimal collaboration policies. One …
long been applied to multiagent systems in order to learn optimal collaboration policies. One …
Photoexcited molecular probes for selective and revertible imaging of cellular reactive oxygen species
Y Wen, Z Long, F Huo, C Yin - Organic Chemistry Frontiers, 2021 - pubs.rsc.org
Redox homeostasis is key to maintaining the normal physiological status of living cells. The
redox state of cells is primarily a consequence of the precise balance between levels of …
redox state of cells is primarily a consequence of the precise balance between levels of …
[HTML][HTML] Chinese patient with cerebrotendinous xanthomatosis confirmed by genetic testing: A case report and literature review
LX Cao, M Yang, Y Liu, WY Long… - World Journal of Clinical …, 2020 - ncbi.nlm.nih.gov
BACKGROUND Cerebrotendinous xanthomatosis (CTX) is a treatable autosomal recessive
inherited metabolic disorder. It results from a deficiency of sterol 27-hydroxylase (CYP27A1), …
inherited metabolic disorder. It results from a deficiency of sterol 27-hydroxylase (CYP27A1), …
Specific fluorescence release based on synergistic activation of enzymes and position-dependent of electrophilic groups to diagnose intrahepatic cholestasis of …
Y Wen, Z Long, X Bai, F Huo, C Yin - Chemical Engineering Journal, 2022 - Elsevier
The early diagnosis and effective treatment of disease have presented new challenges to
today's researchers. Recently, an important direction of the development of the fluorescent …
today's researchers. Recently, an important direction of the development of the fluorescent …
Novel strategy for accurate tumor labeling: endogenous metabolic imaging through metabolic probes
Y Wen, Z Long, F Huo, C Yin - Science China Chemistry, 2022 - Springer
Altered metabolism has long been recognized as a central hallmark of cancer; however, in
the fluorescence imaging field, few studies have been conducted to label tumors by exploiting …
the fluorescence imaging field, few studies have been conducted to label tumors by exploiting …