Salvianolic acid B attenuates brain damage and inflammation after traumatic brain injury in mice

T Chen, WB Liu, XD Chao, L Zhang, Y Qu, JL Huo… - Brain research …, 2011 - Elsevier
Salvianolic acid B (SalB), a bioactive compound isolated from the Chinese medicinal herb
Danshen, has been shown to exert various anti-oxidative and anti-inflammatory activities in in …

Beneficial effects of hydrogen gas in a rat model of traumatic brain injury via reducing oxidative stress

X Ji, W Liu, K Xie, W Liu, Y Qu, X Chao, T Chen, J Zhou… - Brain Research, 2010 - Elsevier
Traumatic brain injury (TBI) is a leading cause of mortality and disability among the young
population. It has been shown that hydrogen gas (H 2 ) exerts a therapeutic antioxidant activity …

Neuroprotective effect of osthole against acute ischemic stroke on middle cerebral ischemia occlusion in rats

X Chao, J Zhou, T Chen, W Liu, W Dong, Y Qu, X Jiang… - Brain Research, 2010 - Elsevier
Osthole, a natural coumarin derivative, has taken considerable attention because of its diverse
pharmacological functions. It has been reported to be useful in the treatment of chronic …

VEGF protects rat cortical neurons from mechanical trauma injury induced apoptosis via the MEK/ERK pathway

Y Ma, W Liu, Y Wang, X Chao, Y Qu, K Wang… - Brain research bulletin, 2011 - Elsevier
Traumatic brain injury (TBI) is a serious insult that frequently leads to neurological dysfunction
or death. Vascular endothelial growth factor (VEGF) is a major regulator of angiogenesis …

Up-regulation of heme oxygenase-1 attenuates brain damage after cerebral ischemia via simultaneous inhibition of superoxide production and preservation of NO …

XD Chao, YH Ma, P Luo, L Cao, WB Lau, BC Zhao… - Experimental …, 2013 - Elsevier
Cerebral ischemia exacerbates neuronal death and neurological dysfunction. Evidence
supports the involvement of oxidative/nitrative stress in the pathophysiology of cerebral ischemia…

The role of excitatory amino acid transporters in cerebral ischemia

X Chao, F Fei, Z Fei - Neurochemical research, 2010 - Springer
Glutamate is an excitatory neurotransmitter that plays a major role in the pathogenesis of
ischemia brain injury. The regulation of glutamate neurotransmission is carried out by excitatory …

Activation of Peroxisome Proliferator–activated Receptor β/δ Attenuates Acute Ischemic Stroke on Middle Cerebral Ischemia Occlusion in Rats

X Chao, C Xiong, W Dong, Y Qu, W Ning, W Liu… - Journal of Stroke and …, 2014 - Elsevier
Background Peroxisome proliferator–activated receptor (PPAR)-β/δ is a transcription factor
that belongs to the nuclear hormone receptor family. There is little information about the …

Protective effect of Homer 1a on tumor necrosis factor-α with cycloheximide-induced apoptosis is mediated by mitogen-activated protein kinase pathways

P Luo, Y Zhao, D Li, T Chen, S Li, X Chao, W Liu… - Apoptosis, 2012 - Springer
Although Homer 1, of the postsynaptic density, regulates apoptosis, the signaling
mechanisms are not fully elucidated. In this study, we found that tumor necrosis factor-α (TNF-α)/…

Primary frontoparietal lobe convexity germinoma with dural invasion mimics meningioma

X Ji, X Chao, Z Fei, Y Zhao - Neurosciences Journal, 2011 - nsj.org.sa
Intracranial germinomas are rare and account for only 0.4-3.4% of primary intracranial tumors.
They develop mainly in the midline structures in adolescents. The pineal gland is the most …

Associations between Acute Exposures to PM2. 5 and Carbon Dioxide Indoors and Cognitive Function in Office Workers

…, ER Jones, AS Young, LJ Chen, X Chao… - ISEE Conference …, 2021 - ehp.niehs.nih.gov
BACKGROUND AND AIM: Despite the growing evidence of the effects of air pollution on
cognitive function, there is scarce information about the acute effects of indoor air pollution on …