[HTML][HTML] Differentiation of glial cells from hiPSCs: potential applications in neurological diseases and cell replacement therapy

W Zheng, Q Li, C Zhao, Y Da, HL Zhang… - Frontiers in cellular …, 2018 - frontiersin.org
Glial cells are the most abundant cell type in the central nervous system (CNS) and play
essential roles in maintaining brain homeostasis, forming myelin, and providing support and …

[PDF][PDF] The CGG repeat expansion in RILPL1 is associated with oculopharyngodistal myopathy type 4

…, Q Gang, X Guo, Y Wang, J Xi, W Zhu, Y Da… - The American Journal of …, 2022 - cell.com
Recent studies indicate that CGG repeat expansions in LRP12, GIPC1, and NOTCH2NLC
are associated with oculopharyngodistal myopathy (OPDM) types 1, 2, and 3, respectively. …

Mortality of myasthenia gravis: a national population‐based study in China

…, Q Ma, J Li, X Wen, L Wang, Y Da… - Annals of Clinical …, 2023 - Wiley Online Library
Objective As a potentially life‐threatening condition, myasthenia gravis (MG) has limited
epidemiological studies on mortality. We aim to provide demographic distribution, geographical …

Brain MRI features and scoring of leukodystrophy in adult-onset Krabbe disease

…, SH Kim, H Adachi, B Audoin, X Ayrignac, Y Da… - Neurology, 2019 - AAN Enterprises
Objective To perform a systematic analysis and scoring of brain MRI white matter hyperintensities
(WMH) in adult-onset Krabbe disease. Methods We retrospectively collected basic …

[HTML][HTML] Favorable effects of tacrolimus monotherapy on myasthenia gravis patients

…, L Lei, S Su, Y Lu, L Di, M Wang, M Xu, Y Da - Frontiers in …, 2020 - frontiersin.org
Background and Purpose: Tacrolimus (TAC) has been proven to be a rapid-acting, steroid-sparing
agent for myasthenia gravis (MG) therapy. However, evidence related to the …

[HTML][HTML] Integrative multi-omics analysis identifies genetically supported druggable targets and immune cell specificity for myasthenia gravis

…, Y Han, T Chen, Y Zhao, S Zhou, Y Da… - Journal of translational …, 2024 - Springer
Background Myasthenia gravis (MG) is a chronic autoimmune disorder characterized by
fluctuating muscle weakness. Despite the availability of established therapies, the management …

Short-term outcome prediction for myasthenia gravis: an explainable machine learning model

…, L Chu, S Tan, C Zhang, B Bu, Y Da… - Therapeutic …, 2023 - journals.sagepub.com
Background: Myasthenia gravis (MG) is an autoimmune disease characterized by muscle
weakness and fatigability. The fluctuating nature of the disease course impedes the clinical …

Limb girdle muscular dystrophy D3 HNRNPDL related in a Chinese family with distal muscle weakness caused by a mutation in the prion-like domain

…, Y Lu, J Duo, L Lei, Y OuYang, Y Hao, Y Da… - Journal of …, 2019 - Springer
Limb-girdle muscular dystrophies (LGMD) are a group of clinically and genetically heterogeneous
diseases characterized by weakness and wasting of the pelvic and shoulder girdle …

[HTML][HTML] A randomized open-labeled trial of methotrexate as a steroid-sparing agent for patients with generalized myasthenia gravis

…, F Shen, X Wen, Y Lu, W Zhu, M Wang, Y Da - Frontiers in …, 2022 - frontiersin.org
Background and Purpose Two clinical trials assessing the steroid-sparing effect of methotrexate
(MTX) yielded conflicting results. Our objective was to investigate whether MTX would …

[HTML][HTML] Beyond the motor cortex: thalamic iron deposition accounts for disease severity in amyotrophic lateral sclerosis

Q Li, W Zhu, X Wen, Z Zang, Y Da, J Lu - Frontiers in neurology, 2022 - frontiersin.org
Objective Previous studies have reliably identified iron deposition in the motor cortex as
potential pathogenesis of amyotrophic lateral sclerosis (ALS). Here, we intended to investigate …