Long nanopore reads are advantageous in de novo genome assembly. However, nanopore
reads usually have broad error distribution and high-error-rate subsequences. Existing error …

Although long-read single-cell RNA isoform sequencing (scISO-Seq) can reveal alternative
RNA splicing in individual cells, it suffers from a low read throughput. Here, we introduce HIT-…

A novel severe acute respiratory syndrome (SARS)-associated coronavirus (SARS-CoV)
has been identified as the aetiological agent of SARS. We previously isolated and …

Although long Nanopore reads are advantageous in de novo genome assembly, applying
Nanopore reads in genomic studies is still hindered by their complex errors. Here, we …

Single-cell isoform sequencing can reveal transcriptomic dynamics in individual cells invisible
to bulk- and single-cell RNA analysis based on short-read sequencing. However, current …

Ischemic stroke (IS) accounts for most of the cases of stroke onset, and due to short
therapeutic time window for thrombolysis and numerous limited treatment measures and …

MicroRNAs (miRNAs/miRs) are sensitive biomarkers and endogenous repressors of gene
expression by decreasing mRNA stability and interfering with mRNA translation. Despite a …

OBJECTIVE: To investigate the mechanisms and protective effects of allicin on learning and
memory in a mouse model of Alzheimer’s disease (AD). METHODS: This study took place in …

To evaluate the screening performance of individual and combined use of clinical breast
examination, ultrasonography and mammography in Chinese women, we conducted a biennial …

Insight into the current status of long-term care facilities (LTCFs) and chronic diseases in
underdeveloped areas in China is scant. Using a census method to survey older adults ≥60 …