Mesenchymal stem cells (MSCs) are of special interest due their potential clinical use in cell-based
therapy. Therapies engaging MSCs are showing increasing promise in the cancer …

The transcription factor nuclear factor-κB (NF-κB) is a critical regulator of the immune response,
inflammation, cell growth, and survival. Canonical and non-canonical pathways, two NF-…

Stem cells, especially mesenchymal stem cells (MSCs)-based therapies have been greatly
attentioned in regenerative medicine through multi-lineage differentiation, self-renewal …

Drug resistance in cancer, especially in leukemia, creates a dilemma in treatment planning.
Consequently, studies related to the mechanisms underlying drug resistance, the molecular …

The Ral (Ras‐Like) signaling pathway plays an important role in the biology of cells. A plethora
of effects is regulated by this signaling pathway and its prooncogenic effectors. Our team …

Cost-efficient sensitive detection of solid tumor markers in patients’ serums with high accuracy
and specificity has been a striking challenge. The early detection of ovarian cancer (OC) …

Purpose: The effect of mesenchymal stem cells (MSCs) on the immortality features of
malignant cells, such as hematologic cancerous cells, are controversial, and the associated …

Background: Caspases proteins are protease enzymes involved in the initiation and execution
of apoptosis process. Regulation of apoptosis process plays an important role in the …

As genetically engineered cells, chimeric antigen receptor (CAR)-T cells express specific
receptors on their surface to target and eliminate malignant cells. CAR proteins are equipped …

… Zohreh Sanaat helped to select the study participants. Versions of the manuscripts were
shared, revised and written by all authors. All authors have read and approved the submitted …