[HTML][HTML] A phase 1, open-label study of LCAR-B38M, a chimeric antigen receptor T cell therapy directed against B cell maturation antigen, in patients with relapsed or …

…, Y Xu, XG Wang, RL Zhang, LL Wei, ZF Li, ZZ Li… - Journal of hematology & …, 2018 - Springer
Background Chimeric antigen receptor (CAR) T cell therapy has demonstrated proven
efficacy in some hematologic cancers. We evaluated the safety and efficacy of LCAR-B38M, a …

MicroRNA profiling of human gastric cancer

Y Yao, AL Suo, ZF Li, LY Liu… - Molecular …, 2009 - spandidos-publications.com
MicroRNAs are a group of small non-coding RNAs that modulate gene expression. The de-regulation
of microRNA expression has been found in several types of cancer. To study the …

Chemokines and their receptors promoting the recruitment of myeloid-derived suppressor cells into the tumor

BH Li, MA Garstka, ZF Li - Molecular immunology, 2020 - Elsevier
Myeloid-derived suppressor cells (MDSCs) expand in tumor-bearing host. They suppress
anti-tumor immune response and promote tumor growth. Chemokines play a vital role in …

[HTML][HTML] Long-term follow-up of a phase 1, first-in-human open-label study of LCAR-B38M, a structurally differentiated chimeric antigen receptor T (CAR-T) cell therapy …

…, J Bai, Y Xu, XG Wang, RL Zhang, LL Wei, ZF Li… - Blood, 2019 - Elsevier
Background: In RRMM, the median overall survival (OS) of pts with RRMM who progressed
after exposure to ≥3 prior therapies is ~13 mo, indicating a high unmet need. LCAR-B38M is …

[HTML][HTML] Inhibitory effects of saikosaponin-d on CCl4-induced hepatic fibrogenesis in rats

…, YA Cheng, P Song, ZG Liu, ZF Li - World journal of …, 2007 - ncbi.nlm.nih.gov
AIM: To investigate the suppressive effect of saikosaponin-d (SSd) on hepatic fibrosis in rats
induced by CCl 4 injections in combination with alcohol and high fat, low protein feeding …

Transmission patterns of COVID-19 in the mainland of China and the efficacy of different control strategies: a data-and model-driven study

J Zu, ML Li, ZF Li, MW Shen, YN Xiao… - Infectious diseases of …, 2020 - mednexus.org
Background: The coronavirus disease 2019 (COVID-19) outbreak has seriously endangered
the health and lives of Chinese people. In this study, we predicted the COVID-19 epidemic …

[HTML][HTML] Scutellaria barbate extract induces apoptosis of hepatoma H22 cells via the mitochondrial pathway involving caspase-3

ZJ Dai, XJ Wang, ZF Li, ZZ Ji, HT Ren… - World Journal of …, 2008 - ncbi.nlm.nih.gov
AIM: To study the growth inhibitory and apoptotic effects of Scutellaria barbata D. Don (S.
barbata) and to determine the underlying mechanism of its antitumor activity in mouse liver …

[HTML][HTML] Calcium signaling of pancreatic acinar cells in the pathogenesis of pancreatitis

J Li, R Zhou, J Zhang, ZF Li - World Journal of Gastroenterology …, 2014 - ncbi.nlm.nih.gov
Pancreatitis is an increasingly common and sometimes severe disease that lacks a specific
therapy. The pathogenesis of pancreatitis is still not well understood. Calcium (Ca 2+) is a …

[HTML][HTML] Spleen contributes to restraint stress induced changes in blood leukocytes distribution

W Jiang, YU Li, J Sun, L Li, J Li, C Zhang, C Huang… - Scientific Reports, 2017 - nature.com
Psychological stress has great impacts on the immune system, particularly the leukocytes
distribution. Although the impacts of acute stress on blood leukocytes distribution are well …

[HTML][HTML] Preferential inhibition of hepatocellular carcinoma by the flavonoid Baicalein through blocking MEK-ERK signaling

…, S Zhang, JA Qi, ZD Wang, J Li… - International …, 2012 - spandidos-publications.com
Baicalein is a purified flavonoid extracted from the roots of Scutellaria baicalensis or Scutellaria
radix. Although previous studies have suggested that Baicalein possesses an in vitro anti…