[HTML][HTML] Anti-cerebral ischemia reperfusion injury of polysaccharides: A review of the mechanisms

Q Yuan, Y Yuan, Y Zheng, R Sheng, L Liu, F Xie… - Biomedicine & …, 2021 - Elsevier
Cerebral ischemia-reperfusion injury can lead to a series of serious brain diseases and
cause death or different degrees of disability. Polysaccharide is a kind of biological …

[HTML][HTML] Hydrogen gas attenuates hypoxic-ischemic brain injury via regulation of the MAPK/HO-1/PGC-1a pathway in neonatal rats

P Wang, M Zhao, Z Chen, G Wu, M Fujino… - … Medicine and Cellular …, 2020 - hindawi.com
Neonatal hypoxic-ischemic encephalopathy (HIE) is a leading cause of death in neonates
with no effective treatments. Recent advancements in hydrogen (H 2) gas offer a promising …

Lycium barbarum Polysaccharide Prevents Focal Cerebral Ischemic Injury by Inhibiting Neuronal Apoptosis in Mice

T Wang, Y Li, Y Wang, R Zhou, L Ma, Y Hao, S Jin… - PloS one, 2014 - journals.plos.org
Aims of the Study To investigate the neuroprotective effect of Lycium barbarum
polysaccharide (LBP) on focal cerebral ischemic injury in mice and to explore its possible …

Oxymatrine attenuated hypoxic-ischemic brain damage in neonatal rats via improving antioxidant enzyme activities and inhibiting cell death

P Zhao, R Zhou, HN Li, WX Yao, HQ Qiao… - Neurochemistry …, 2015 - Elsevier
Oxymatrine (OMT), an active constituent of Chinese herb Sophora flavescens Ait, has been
proved to possess anti-tumor, anti-oxidant, anti-inflammatory, and anti-apoptotic activities …

Downregulated RASD1 and upregulated miR-375 are involved in protective effects of calycosin on cerebral ischemia/reperfusion rats

Y Wang, X Dong, Z Li, W Wang, J Tian… - Journal of the neurological …, 2014 - Elsevier
Isoflavone calycosin is a typical phytoestrogen extracted from Chinese medical herb Radix
Astragali. It has been reported that estrogens could provide neuroprotective effects, and …

Method parameters' impact on mortality and variability in rat stroke experiments: a meta-analysis

JO Ström, E Ingberg, A Theodorsson, E Theodorsson - BMC neuroscience, 2013 - Springer
Background Even though more than 600 stroke treatments have been shown effective in
preclinical studies, clinically proven treatment alternatives for cerebral infarction remain …

Hepatoprotective effects of Yulangsan flavone against carbon tetrachloride (CCl4)-induced hepatic fibrosis in rats

Y Guo, X Liang, M Meng, H Chen, X Wei, M Li, J Li… - Phytomedicine, 2017 - Elsevier
Background Yulangsan flavone (YLSF) was extracted from the root of Millettia pulchra Kurz
var-laxior (Dunn) Z. Wei, which has been widely used for liver disease treatment in the …

Oxysophoridine protects against focal cerebral ischemic injury by inhibiting oxidative stress and apoptosis in mice

TF Wang, Z Lei, YX Li, YS Wang, J Wang… - Neurochemical …, 2013 - Springer
Our previous studies have demonstrated that oxysophoridine (OSR) has protective effects
on cerebral neurons damage in vitro induced by oxygen and glucose deprivation. In this …

GPR17 receptor modulators and their therapeutic implications: review of recent patents

G Marucci, D Dal Ben, C Lambertucci… - Expert Opinion on …, 2019 - Taylor & Francis
Introduction: The GPR17 receptor, phylogenetically related to both purinergic P2Y and
CysLT receptors, is mainly expressed in the CNS and, in general, in organs that can typically …

Effects of polysaccharides of the Euphoria Longan (Lour.) Steud on focal cerebral ischemia/reperfusion injury and its underlying mechanism

J Chen, X Chen, J Qin - Brain injury, 2011 - Taylor & Francis
Objective: To investigate the effects of polysaccharides of the Euphoria Longan (Lour.)
Steud on focal cerebral ischemia/reperfusion (I/R) injury in rats. Methods: In this study …