So far, no coherent and convincing theory has been developed to fully explain the
pathogenesis of migraine, although many researchers and experts emphasize its …

Magnesium deficiency may occur for several reasons, such as inadequate intake or
increased gastrointestinal or renal loss. A large body of literature suggests a relationship …

Magnesium deficiency is prevalent in women of childbearing age in both developing and
developed countries. The need for magnesium increases during pregnancy, and the …

Migraine is a highly prevalent and disabling primary headache disorder, however its
pathophysiology remains unclear, hindering successful treatment. A number of key …

Background: Migraine is a common neurological disorder and is affected by nutrients.
Calcium and magnesium are essential minerals that play an important role in nerve function …

The pro-nociceptive role of glutamate in the CNS in migraine pathophysiology is well
established. Glutamate, released from trigeminal afferents, activates second order …

Headache is the most frequent neurological symptom and the most prevalent pain in
children and adolescents, and constitutes a serious health problem that may lead to …

Background: Magnesium (Mg) is an essential element for the body. It is a cofactor for ATP,
DNA, and RNA and more than 600 enzymes. As it is similar to Ca 2+, this element can also …

Background Migraine is an incompletely understood, debilitating disorder that lacks a
universally effective treatment. Magnesium participates in a variety of biochemical processes …

Simple Summary What is already known: Mg2+ levels modulate the affinity of oxytocin
receptors for oxytocin in vitro, low serum Mg2+ is correlated with migraine headache onset …