Post-stroke cognitive impairment occurs frequently in the patients with stroke. The
prevalence of post-stroke cognitive impairment ranges from 20% to 80%, which varies for …

Alzheimer's disease (AD) is the most prevalent form of dementia which affects people older
than 60 years of age. In AD, the dysregulation of the amyloid-beta (Aβ) level leads to the …

Amyloid-β (Aβ) and tau proteins currently represent the two most promising targets to treat
Alzheimer's disease. The most extensively developed method to treat the pathologic forms of …

Alzheimer's disease (AD) is a primary cause of dementia in the middle-aged and elderly
worldwide. Animal models for AD are widely used to study the disease mechanisms as well …

Mitochondria are important for providing cellular energy ATP through the oxidative
phosphorylation pathway. They are also critical in regulating many cellular functions …

Objective To investigate the association between visit-to-visit variability in blood pressure
and cognitive function in old age (> 70 years). Design Prospective cohort study. Setting …

Type 2 diabetes mellitus (T2DM) is a chronic disease that has reached the levels of a global
epidemic. In order to achieve optimal glucose control, it is often necessary to rely on …

The essential trace element, selenium (Se), is crucial to the brain but it may be potentially
neurotoxic, depending on dosage and speciation; Se has been discussed for decades in …

Alzheimer disease (AD) is a medically and financially overwhelming condition, and
incidence rates are expected to triple by 2050. Despite decades of research in animal …

The aim of the present review is to discuss traditional hypotheses on the etiopathogenesis of
Alzheimer's disease (AD), as well as the role of metabolic-syndrome-related mechanisms in …