Although the GABAergic benzodiazepines (BZDs) and Z-drugs (zolpidem, zopiclone, and
zaleplon) are FDA-approved for insomnia disorders with a strong evidence base, they have …

Paradoxical insomnia is characterized by discrepancy between subjective and objective
assessments of sleep and is challenging to diagnosis and treat. Typically …

The state of sleep consists of different phases that proceed in successive, tightly regulated
order through the night forming a physiological program, which for each individual is …

Opinion Statement Olanzapine has become a major drug in the management of
chemotherapy-induced nausea and vomiting as a prophylactic agent. In addition, a recent …

Background Obstructive sleep apnea (OSA) and alcohol-related diseases (ARDs), including
alcohol use disorder, alcohol-related psychiatric disorders, alcoholic liver disease, alcoholic …

Study Objectives: Patients with chronic insomnia may respond differently to therapeutic
modalities. This study examined differences in response of individuals with 2 insomnia …

Background: Cancer patients often experience symptoms such as anorexia, anxiety and
insomnia, which can impact their quality of life. Randomized placebo-controlled trials …

Background: Sleep disturbance is a common self-reported complaint by PTSD patients.
However, there are controversies in documenting objective indices of disrupted sleep in …

Background With increasing use of atypical antipsychotic (AAP) agents, the concern has
been raised about the association between AAP agents and medical complications …

New derivatives of the known antipsychotic drug olanzapine have been obtained as
potential compounds with anticancer activity in two metabolically different breast cancer cell …