Oxidative stress: major threat in traumatic brain injury

N Khatri, M Thakur, V Pareek, S Kumar… - CNS & Neurological …, 2018 - ingentaconnect.com
Background & Objective: Traumatic Brain Injury (TBI) is one of the major causes of mortality
and morbidity worldwide. It represents mild, moderate and severe effects of physical assault …

[HTML][HTML] Role of interleukin-10 in acute brain injuries

JM Garcia, SA Stillings, JL Leclerc, H Phillips… - Frontiers in …, 2017 - frontiersin.org
Interleukin-10 (IL-10) is an important anti-inflammatory cytokine expressed in response to
brain injury, where it facilitates the resolution of inflammatory cascades, which if prolonged …

[HTML][HTML] Traumatic brain injury imaging in the second near-infrared window with a molecular fluorophore

X Zhang, H Wang, AL Antaris, L Li, S Diao… - … (Deerfield Beach, Fla …, 2016 - ncbi.nlm.nih.gov
Traumatic brain injury (TBI) is a leading cause of death and disability worldwide, therefore
important to understanding pathogenesis. Here, we designed a bright, renal-excreted and …

Recent advances in pathophysiology of traumatic brain injury

P Kaur, S Sharma - Current neuropharmacology, 2018 - ingentaconnect.com
Background: Traumatic brain injury (TBI) constitutes the primary reason for mortality and
morbidity in persons worldwide below 45 years of age. 1.7 million Traumatic events occur …

[HTML][HTML] Antioxidant therapies in traumatic brain injury

V Di Pietro, KM Yakoub, G Caruso, G Lazzarino… - Antioxidants, 2020 - mdpi.com
Due to a multiplicity of causes provoking traumatic brain injury (TBI), TBI is a highly
heterogeneous pathology, characterized by high mortality and disability rates. TBI is an …

[HTML][HTML] Modeling traumatic brain injury in human cerebral organoids

S Ramirez, A Mukherjee, S Sepulveda… - Cells, 2021 - mdpi.com
Traumatic brain injury (TBI) is a head injury that disrupts the normal brain structure and
function. TBI has been extensively studied using various in vitro and in vivo models. Most of …

[HTML][HTML] Dexmedetomidine inhibits inflammatory response and autophagy through the circLrp1b/miR-27a-3p/Dram2 pathway in a rat model of traumatic brain injury

H Li, C Lu, W Yao, L Xu, J Zhou, B Zheng - Aging (Albany NY), 2020 - ncbi.nlm.nih.gov
Circular RNAs (circRNAs) have a regulatory function on inflammation and autophagy, of
which rno-circRNA_010705 (circLrp1b) appears to be significantly up-regulated following …

[HTML][HTML] The effect of concomitant peripheral injury on traumatic brain injury pathobiology and outcome

SJ McDonald, M Sun, DV Agoston… - Journal of …, 2016 - Springer
Background Traumatic injuries are physical insults to the body that are prevalent worldwide.
Many individuals involved in accidents suffer injuries affecting a number of extremities and …

Sodium butyrate exerts neuroprotective effects by restoring the blood-brain barrier in traumatic brain injury mice

H Li, J Sun, F Wang, G Ding, W Chen, R Fang, Y Yao… - Brain research, 2016 - Elsevier
Sodium butyrate (SB) has been widely used to treat cerebral diseases. The aim of the
present study is to examine the neuroprotective effects of SB on early TBI in mice and to …

[HTML][HTML] Dietary (poly) phenols in traumatic brain injury

R Carecho, D Carregosa, BO Ratilal, I Figueira… - International Journal of …, 2023 - mdpi.com
Traumatic brain injury (TBI) remains one of the leading causes of death and disability in
young adults worldwide. Despite growing evidence and advances in our knowledge …