Compared to other organs, the brain is especially exposed to oxidative stress. In general,
brains from young females tend to present lower oxidative damage in comparison to their …

The prevalence of psychiatric disorders permanently increases. Polyphenolic compounds
can be involved in modulation of mental health including brain plasticity, behaviour, mood …

Development of new medications is a lengthy and costly process, and drug repositioning
might help to shorten the development cycle. We present a machine learning (ML) workflow …

Schizophrenia continues to be an illness with poor outcome. Most mechanistic changes
occur many years before the first episode of schizophrenia; these are not reversible after the …

Schizophrenia is a chronic mental and behavioral disorder characterized by clusters of
symptoms including hallucinations, delusions, disorganized thoughts and social withdrawal …

Countless bioactive constituents obtained from different medicinal plants have long been
focused by the researchers of the scientific community and pharmaceutical industry. In …

Development of new medications is a very lengthy and costly process. Finding novel
indications for existing drugs, or drug repositioning, can serve as a useful strategy to shorten …

The observation that a person's sex influences the onset age of schizophrenia, the course of
the disease, and antipsychotic treatment response suggests a possible role for estrogen …

Central nervous system (CNS) disorders are a serious health problem worldwide. There are
a wide variety of CNS disorders, and plant‐based polyphenols have been widely explored …

Computational analysis reveals the therapeutic potential of Asiatic acid against the miRNA
correlated differentially expressed g Page 1 AIMS Molecular Science, 11(2): 99–115. DOI …