[HTML][HTML] Intracerebral hemorrhage, oxidative stress, and antioxidant therapy

X Duan, Z Wen, H Shen, M Shen, G Chen - Oxidative medicine and …, 2016 - hindawi.com
Hemorrhagic stroke is a common and severe neurological disorder and is associated with
high rates of mortality and morbidity, especially for intracerebral hemorrhage (ICH) …

[HTML][HTML] Pathophysiological mechanisms and potential therapeutic targets in intracerebral hemorrhage

Z Shao, S Tu, A Shao - Frontiers in pharmacology, 2019 - frontiersin.org
Intracerebral hemorrhage (ICH) is a subtype of hemorrhagic stroke with high mortality and
morbidity. The resulting hematoma within brain parenchyma induces a series of adverse …

[HTML][HTML] Matrix metalloproteinases in acute intracerebral hemorrhage

S Lattanzi, M Di Napoli, S Ricci, AA Divani - Neurotherapeutics, 2020 - Elsevier
Spontaneous intracerebral hemorrhage (ICH) accounts for 10–30% of all strokes and affects
more than one million people every year worldwide, and it is the stroke subtype associated …

[HTML][HTML] The injury and therapy of reactive oxygen species in intracerebral hemorrhage looking at mitochondria

J Qu, W Chen, R Hu, H Feng - Oxidative medicine and cellular …, 2016 - hindawi.com
Intracerebral hemorrhage is an emerging major health problem often resulting in death or
disability. Reactive oxygen species (ROS) have been identified as one of the major …

Programmed cell death after intracerebral hemorrhage

T Bobinger, P Burkardt, HB Huttner… - Current …, 2018 - ingentaconnect.com
Background: Intracerebral hemorrhage (ICH) accounts for up to 15% of all strokes and is
characterized by high rates of mortality and morbidity. The post-ICH brain injury can be …

Thrombin enhanced matrix metalloproteinase-9 expression and migration of SK-N-SH cells via PAR-1, c-Src, PYK2, EGFR, Erk1/2 and AP-1

CC Yang, LD Hsiao, CM Yang, CC Lin - Molecular neurobiology, 2017 - Springer
Neuroinflammation is a hallmark of neurodegenerative disorders in the central nerve system
(CNS). Thrombin has been known as one of the factors in pathological processes including …

Y-2 reduces oxidative stress and inflammation and improves neurological function of collagenase-induced intracerebral hemorrhage rats

Y Hua, L Zhou, W Yang, W An, X Kou, J Ren… - European Journal of …, 2021 - Elsevier
Intracerebral hemorrhage (ICH) is a devastating disease, and there is currently no specific
pharmacological treatment that can improve clinical outcomes. Y-2 sublingual tablets, each …

Edaravone Maintains AQP4 Polarity Via OS/MMP9/β-DG Pathway in an Experimental Intracerebral Hemorrhage Mouse Model

Z Wang, Y Li, Z Wang, Y Liao, Q Ye, S Tang… - Molecular …, 2024 - Springer
Oxidative stress (OS) is the main cause of secondary damage following intracerebral
hemorrhage (ICH). The polarity expression of aquaporin-4 (AQP4) has been shown to be …

Influence of nanoparticle-loaded edaravone on postoperative effects in patients with cerebral hemorrhage

L Dang, X Dong, J Yang - Journal of Nanoscience and …, 2021 - ingentaconnect.com
In order to explore the influence of nanoparticle-loaded edaravone on postoperative effects
in patients with cerebral hemorrhage, a total of 120 patients who were diagnosed as …

[HTML][HTML] Correlations of acute cerebral hemorrhage complicated with stress ulcer bleeding with acute physiology and chronic health evaluation (APACHE) II score …

X Wang, N Shi, H Shi, H Ye, N Li, P Sun… - … Medical Journal of …, 2018 - ncbi.nlm.nih.gov
Background This study investigated the correlations between acute cerebral hemorrhage
complicated with stress ulcer bleeding and corresponding indexes, including the Acute …