Objective This study investigated the biochemical, histopathological and physiological
effects of Citrullus colocynthis on peripheral neuropathy in rats with streptozotocin (STZ) …

The current protocols for neuropathic pain management include µ-opioid receptor (MOR)
analgesics alongside other drugs; however, there is debate on the effectiveness of opioids …

Neuropathy is a common complication of diabetes affecting a large number of people
worldwide. Triphala churna is a formulation mentioned in Ayurveda-a traditional system of …

The peripheral nervous system is one of many organ systems that can be profoundly
impacted in diabetes mellitus. Diabetic peripheral neuropathy has a significant negative …

Background Diabetic neuropathy is one of the most common microvascular complication of
diabetes. It is associated with neuronal dysfunction and pain. Paeonol is an important …

Pain is one of the most common symptoms experienced by patients. The use of current
analgesics is limited by low efficacy and important side effects. Transient receptor potential …

Despite the large arsenal of analgesic medications, neuropathic pain (NP) management is
not solved yet. Angiotensin II receptor type 1 (AT1) has been identified as a potential target …

Neuropathic Pain is caused by damage to a nerve or disease of the somatosensory nervous
system. Apart from the blood pressure regulating actions of angiotensin ligands, studies …

In the majority of patients with breast cancer in the advanced stages, skeletal metastases are
common, which may cause excruciating pain. Currently available drug treatments for relief of …

Aim Inflammatory cascade and oxidative stress play a central role in diabetic peripheral
neuropathy via activation of inflammatory cytokines. Escin has potent antioxidant and anti …