Multiple sclerosis (MS) is an autoimmune, demyelinating disease of the central nervous
system (CNS). It predominantly affects young women and is one of the most common causes …

The increasing life expectancy has led to a higher incidence of age-related
neurodegenerative conditions. Within this framework, neuroinflammation emerges as a …

Abstract Rationale: The FDA-approved Dimethyl Fumarate (DMF) as an oral drug for
Multiple Sclerosis (MS) treatment based on its immunomodulatory activities. However, it also …

Multiple sclerosis (MS) is a chronic autoimmune disease caused by an insufficient
suppression of autoreactive T lymphocytes. One reason for the lack of immunological control …

Abstract Introduction Multiple Sclerosis (MS) is a debilitating neurodegenerative disease in
which demyelination due to auto-inflammation is considered to be the underlying …

Förster resonance energy transfer (FRET) continues to be a useful tool to study movement
and interaction between proteins within living cells. When FRET as an optical technique is …

Background: People with chronic illnesses have increased morbidity and mortality
associated with COVID-19 infection. The influence of a person's serious and/or comorbid …

Bone marrow-derived neural stem cells (BM-NSCs) have therapeutic effect on EAE, an
animal model of multiple sclerosis. However, the beneficial effect is suboptimal due to the …

Autoimmune diseases are increasingly recognized as disease entities in which
dysregulated cytokines contribute to tissue-specific inflammation. In organ-specific and …

Autoimmune diseases (AID) are characterized by inappropriate immune reaction against
one or more of the organism's own tissues [1],[2]. This is based on humoral (autoantibodies …