Efficacy and safety of levetiracetam vs. phenobarbital for neonatal seizures: a systematic review and meta-analysis
MY Qiao, HT Cui, LZ Zhao, JK Miao… - Frontiers in Neurology, 2021 - frontiersin.org
Background: Neonatal seizures are a common neurological emergency in newborns.
Phenobarbital (PB) is the first-line antiepileptic drug (AED). However, PB has some side …
Phenobarbital (PB) is the first-line antiepileptic drug (AED). However, PB has some side …
Why we urgently need improved seizure and epilepsy therapies for children and neonates
RM Pressler, L Lagae - Neuropharmacology, 2020 - Elsevier
In contrast to epilepsy in adolescents and adults, neonatal seizures and early onset epilepsy
poses unique challenges with significant repercussion for treatment choices. Most …
poses unique challenges with significant repercussion for treatment choices. Most …
A comparison of levetiracetam and phenobarbital for the treatment of neonatal seizures associated with hypoxic–ischemic encephalopathy
LM Rao, SA Hussain, T Zaki, A Cho, T Chanlaw… - Epilepsy & Behavior, 2018 - Elsevier
Purpose Seizures are common in term infants with hypoxic–ischemic encephalopathy (HIE)
undergoing therapeutic hypothermia. Although phenobarbital (PHB) is generally considered …
undergoing therapeutic hypothermia. Although phenobarbital (PHB) is generally considered …
Recent advances in the diagnosis and treatment of neonatal seizures
D Samanta - Neuropediatrics, 2021 - thieme-connect.com
Seizures are the most common neurological emergency in the neonates, and this age group
has the highest incidence of seizures compared with any other period of life. The author …
has the highest incidence of seizures compared with any other period of life. The author …
Anti‐seizure medications for neonates with seizures
T Abiramalatha, S Thanigainathan… - Cochrane Database …, 2023 - cochranelibrary.com
Background Newborn infants are more prone to seizures than older children and adults. The
neuronal injury caused by seizures in neonates often results in long‐term …
neuronal injury caused by seizures in neonates often results in long‐term …
[HTML][HTML] Levetiracetam versus phenytoin for the treatment of established status epilepticus: a systematic review and meta-analysis of randomized controlled trials
Objectives To compare the efficacy and safety of levetiracetam and phenytoin for the
treatment of established status epilepticus. Methods In this systematic review, we searched …
treatment of established status epilepticus. Methods In this systematic review, we searched …
Efficacy of Levetiracetam in neonatal seizures: a systematic review
D Sharma, AM Hussain, SS Sharma - The Journal of Maternal-Fetal …, 2022 - Taylor & Francis
Background Neonatal seizures represent the most frequent presenting sign of any
neurological abnormality secondary to various etiologies in the neonatal period …
neurological abnormality secondary to various etiologies in the neonatal period …
[HTML][HTML] Levetiracetam monotherapy for the treatment of infants with epilepsy
Purpose Levetiracetam is a broad-spectrum anti-epileptic drug that is effective against both
focal and generalized epilepsies. In this study, we aimed to evaluate the efficacy, tolerability …
focal and generalized epilepsies. In this study, we aimed to evaluate the efficacy, tolerability …
A review on pharmacokinetics of levetiracetam in neonates
A Agrawal, A Banergee - Current Drug Metabolism, 2017 - ingentaconnect.com
Background: Neonatal seizures are the most common clinical manifestation of Central
Nervous System (CNS) dysfunction and are associated with various neurological sequelae …
Nervous System (CNS) dysfunction and are associated with various neurological sequelae …
Efficacy of levetiracetam as first-line therapy for neonatal clinical seizures and neurodevelopmental outcome at 12 months of age
Appropriate treatment of neonatal seizures with an effective therapy is important in reducing
long-term neurologic disabilities. Sixty-seven neonates, who received intravenous (IV) …
long-term neurologic disabilities. Sixty-seven neonates, who received intravenous (IV) …