Rotenone-induced model of parkinson's disease: Beyond mitochondrial complex I inhibition

MT Ibarra-Gutiérrez, N Serrano-García… - Molecular …, 2023 - Springer
Parkinson's disease (PD) is usually diagnosed through motor symptoms that make the
patient incapable of carrying out daily activities; however, numerous non-motor symptoms …

[HTML][HTML] Synucleinopathy in amyotrophic lateral sclerosis: A potential avenue for antisense therapeutics?

B Roberts, F Theunissen, FL Mastaglia… - International Journal of …, 2022 - mdpi.com
Amyotrophic lateral sclerosis (ALS) is the most common adult-onset motor neuron disease
classified as both a neurodegenerative and neuromuscular disorder. With a complex …

Parkinson's disease: risk factor modification and prevention

S Rajan, B Kaas - Seminars in neurology, 2022 - thieme-connect.com
The global burden of Parkinson's disease (PD) has increased from 2.5 to 6.1 million since
the 1990s. This is expected to rise as the world population ages and lives longer. With the …

Role of the Exposome in Neurodegenerative Disease: Recent Insights and Future Directions

SA Sakowski, EJ Koubek, KS Chen… - Annals of …, 2024 - Wiley Online Library
Neurodegenerative diseases are increasing in prevalence and place a significant burden on
society. The causes are multifactorial and complex, and increasing evidence suggests a …

[PDF][PDF] Attenuation of hexaconazole induced oxidative stress by folic acid, malic acid and ferrocenecarboxaldehyde in an invertebrate model Bombyx mori

H Ashraf, A Qamar, N Maheshwari - Heliyon, 2022 - cell.com
Fungicides are a class of pesticides used to ward off fungal diseases from agricultural crops
to achieve maximum productivity. These chemicals are quite efficient in controlling diseases; …

Well-water consumption and risk of Parkinson's disease: a meta-analysis of 15 observational studies

Y Shi, K Zhang, M Ye - Neuropsychiatric Disease and Treatment, 2021 - Taylor & Francis
Introduction The relationship between the risk of Parkinson disease and well-water
consumption has been extensively studied, but the results have been contradictory …

[HTML][HTML] Lifestyle Factors and Parkinson's Disease Risk in a Rural New England Case-Control Study

AS Andrew, FL Anderson, SL Lee… - Parkinson's …, 2021 - hindawi.com
Introduction. Parkinson's disease (PD) is an age-related neurodegenerative disease likely
caused by complex interactions between genetic and environmental risk factors. Exposure …

Molecular insight into the mechanism of action of some beneficial flavonoids for the treatment of Parkinson's Disease

S Biswas, A Mitra, S Roy, R Ghosh, A Bagchi - bioRxiv, 2023 - biorxiv.org
Parkinsons Disease (PD) is a severe neurodegenerative disorder. It is characterized by the
declination of dopaminergic (DA) neurons of substantia nigra pars compacta in the mid …

The Evolving Landscape of Parkinson's Disease Research: Current Challenges and Future Outlook

R Tenchov, J Sasso, QA Zhou - 2024 - chemrxiv.org
Parkinson's disease (PD) is a progressive neurodegenerative disorder that primarily affects
movement. It occurs due to gradual loss of dopamine-producing brain cells, particularly in …

[PDF][PDF] Parkinsonism in a patient with metal on metal total hip replacement related elevated serum heavy metal levels

C Lee, M Hu - Cureus, 2021 - cureus.com
Heavy metal toxicity accounts for a rare minority of parkinsonian presentations. It is
established that metal on metal total hip replacements can elevate serum cobalt and …