OBJECTIVE: To evaluate the effect of Donepezil on cerebral blood flow velocity using non-
invasive transcranial Doppler (TCD) sonography. METHODS: This clinical trial was carried …

Background: The recent introduction of acetylcholinesterase inhibitors (AChEIs) therapy for
Alzheimer's Disease (AD) has led to the need to assess the brain's response to the therapy …

Introduction Donepezil, an acetylcholinesterase inhibitor, has been reported to have an
effect that improves cerebral blood flow (CBF) alongside its primary effect on memory …

ABSTRACT Background and Purpose. Treatment with acetylcholinesterase inhibitors
(AchEIs) is beneficial for patients with Alzheimer's disease (AD). But the clinical response …

Objective Treatment with donepezil improves cognitive function of patients with Alzheimer's
disease (AD) when compared to a placebo-controlled group. The purpose of this study was …

Objective The objective of this study was to elucidate the relationship between the effects of
donepezil hydrochloride (donepezil) and cerebral blood flow, and to evaluate the usefulness …

We attempted to identify the characteristic patterns in regional cerebral blood flow (rCBF) of
patients with Alzheimer's disease who responded to donepezil therapy. Sixty-one patients …

ABSTRACT BACKGROUND We attempt to evaluate objectively the regional cerebral blood
flow (rCBF) changes during long‐term donepezil therapy and the relationship between the …

It has been reported that the cholinesterase inhibitor, donepezil, improves cognitive decline
in patients with Parkinson's disease dementia (PDD). However, this improvement was …

Background: The efficacy of donepezil 10 mg/day against Alzheimer's disease (AD) was
examined, with a primary focus on changes in cerebral blood flow (CBF) as determined by …