An overview of the genetic risk of developing schizophrenia in relatives of schizophrenic patients

AA Al-Jeshi, I Epstein, RB Zipursky - Neurosciences Journal, 2006 - nsj.org.sa
In this article, we review the recent research evidence of genetic risks in the relatives of
patients with schizophrenia, with particular focus on family, twin, adoptive, and gene studies …

A case for returning to multiplex families for further understanding the heritability of schizophrenia: a psychiatrist's perspective

LE DeLisi - Molecular Neuropsychiatry, 2016 - karger.com
The genetic mechanism for schizophrenia still remains unknown despite decades of
research. A tremendous amount of investigator time and effort has gone into ascertainment …

Genetic vulnerability to schizophrenia

RM Murray, AM Reveley, P McGuffin - Psychiatric Clinics of North America, 1986 - Elsevier
The genetic contribution to schizophrenia is the most clearly established etiologic factor.
This article briefly reviews the evidence for a genetic influence as well as recent challenges …

The genetics of schizophrenia

DG Dikeos - Contemporary Neuropsychiatry, 2001 - Springer
On the basis of findings from family, twin, and adoption studies, heredity emerges as a major
etiological factor in the pathogenesis of schizophrenia. Molecular genetic techniques …

[PDF][PDF] Genetics and Schizophrenia: A Comprehensive Clinical Analysis

AU Harisoorya, L D'Mello - researchgate.net
Purpose: Genetics is a significant risk factor for schizophrenia. In the last decade, molecular
genetics research has yielded groundbreaking results, fueling hope for uncovering the basic …

Heredity and environment in schizophrenia, revisited: The contribution of twin and high-risk studies

JR Stabenau, W Pollin - The Journal of nervous and mental …, 1993 - journals.lww.com
Life history study of monozygotic (MZ) twins discordant for schizophrenia led to the 1967
hypothesis that phenotypic schizophrenia was an expression of genotypic vulnerability …

Molecular genetics of schizophrenia

CA Kaufmann, D Malaspina - Psychiatric Annals, 1993 - journals.healio.com
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[HTML][HTML] Is the roller coaster ride in schizophrenia genetics coming to an end? Breakthrough or wishful thinking?

D Rujescu - The World Journal of Biological Psychiatry, 2008 - Taylor & Francis
Family, twin and adoption studies demonstrate evidence for a strong genetic component in
the aetiology of schizophrenia. The relative contribution of genetic factors to the aetiology of …

[HTML][HTML] Genetics of schizophrenia: overview of methods, findings and limitations

MG Henriksen, J Nordgaard… - Frontiers in human …, 2017 - frontiersin.org
Genetics constitute a crucial risk factor to schizophrenia. In the last decade, molecular
genetic research has produced novel findings, infusing optimism about discovering the …

Genetic risk factors for schizophrenia

AG Cardno, MC O'Donovan… - International Journal of …, 2000 - Taylor & Francis
There is substantial evidence that genetic factors contribute to the risk of developing
schizophrenia. To date, most of the evidence for this comes from quantitative genetics, in the …