Use of methylprednisolone in acute spinal injury

AM Alkhani, ASH Ghomraoui - Neurosciences Journal, 2003 - nsj.org.sa
OBJECTIVE: To obtain an appraisal for the use of methylprednisolone (MP) in the early
management of acute spinal cord injury (SCI) in our health system and the attitude to its use …

Methylprednisolone treatment in acute spinal cord injury: the myth challenged through a structured analysis of published literature

FT Sayer, E Kronvall, OG Nilsson - The Spine Journal, 2006 - Elsevier
BACKGROUND CONTEXT: Methylprednisolone has evolved during the 1990s, through the
results obtained from the National Acute Spinal Cord Injury Studies NASCIS II and III, as a …

High-dose methylprednisolone for acute closed spinal cord injury-only a treatment option

H Hugenholtz, DE Cass, MF Dvorak… - Canadian journal of …, 2002 - cambridge.org
Background: A systematic review of the evidence pertaining to methylprednisolone infusion
following acute spinal cord injury was conducted in order to address the persistent confusion …

Methylprednisolone for acute spinal cord injury: an inappropriate standard of care

RJ Hurlbert - Journal of Neurosurgery: spine, 2000 - thejns.org
Object. Since publication in 1990, results from the National Acute Spinal Cord Injury Study II
(NASCIS II) trial have changed the way patients suffering an acute spinal cord injury (SCI) …

[CITATION][C] Methylprednisolone in acute spinal cord injuries—An audit of administration

PA O'Connor, O McCormack, D McCormack, J O'Byrne… - 2002 - Springer
80. Trauma in the West of Ireland, June 1996 to July 2001 — an audit 81. Methylprednisolone in
acute spinal cord injuries — Page 1 27th Sir Peter Freyer Memorial Lecture 2002 in association …

Methylprednisolone in acute spinal cord injuries

PA O'Connor, O McCormack, C Gavin… - Irish journal of medical …, 2003 - Springer
Background Methylprednisolone is the only neuroprotective therapy advocated in acute non-
penetrating spinal cord injury. Trials indicate improved neurological outcome following early …

Current role of methylprednisolone in the treatment of acute spinal cord injury

R Lukáš, I Zýková, P Barsa, J Srám - Acta Chirurgiae Orthopaedicae …, 2011 - europepmc.org
High doses of methylprednisolone (MPSS) came into use as part of a therapeutic protocol
for acute spinal cord injuries following the published results from the NASCIS II study in …

Methylprednisolone in traumatic spinal cord injuries: not proven to be beneficial to the patient at the present time

WP Vandertop, NC Notermans… - Nederlands Tijdschrift Voor …, 1998 - europepmc.org
Ever since the publication in 1990 in The New England Journal of Medicine of a multicentre,
randomised, double-blind, placebo-controlled trial on the efficacy of methylprednisolone …

High dose methylprednisolone in the management of acute spinal cord injury–a systematic review from a clinical perspective

DJ Short, WS El Masry, PW Jones - Spinal cord, 2000 - nature.com
Study design: Systematic literature review for primary data using predefined inclusion,
exclusion and validity criteria. Primary outcome measure was standardised neurological …

Methylprednisolone for acute spinal cord injury: 5-year practice reversal

RJ Hurlbert, MG Hamilton - Canadian journal of neurological …, 2008 - cambridge.org
Objective: To re-evaluate practice patterns for methylprednisolone (MP) administration in
patients with acute spinal cord injury (SCI) within the spinal surgery community across …