There is a growing body of literature that patients on antiepileptic drugs may experience
worsening of seizure control such as increasing frequency, inducing new seizures, refractory …

Phenytoin is the oldest sedative antiepileptic drug and one of the most widely prescribed
antiepileptic drug effective against all types of partial and tonic-clonic seizures except in …

A 81 year-old female, weighing 56 kgs, had taken carbamazepine (10.2 mg/kg/day) for
simple partial motor seizures of recent onset during 15 days. EEG recording showed slow …

Phenytoin is a commonly used antiepileptic drug for various types of seizure disorders
except for absent seizures. Long-term dose-dependent neurological side effects of …

An 18‑year‑old girl (body weight: 30 kg), with epilepsy due to calcified granuloma for 7
years, presented with gradually progressive imbalance and action tremors for 3 weeks. She …

Phenytoin can produce significant dose-related toxicity because of its zero order
pharmacokinetics and is an important issue in pediatric emergency medicine. It is important …

Phenytoin is a commonly used antiepileptic medication in the pediatric age group, but it has
a narrow therapeutic range. Various adverse effects have been reported commonly. We …

In a case of phenytoin (PHT) encephalopathy a correlation was found between rising PHT
serum levels and increase in seizure frequency. Supporting the correlation was the …

Severe cardiac adverse effects are often related to intravenous phenytoin overdose.
However, there is no reported cardiotoxicity resulting from oral overdose of phenytoin. We …

Chronic intoxication of phenytoin (PHT) is a well known cause of cerebellar atrophy or
irreversible cerebellar ataxia. Little attention, on the other hand, is paid for acute PHT …