Objective: To evaluate the therapeutic effects of inhibiting interleukin-1 beta (IL-1β) in vivo
using Anakinra in an experimental model of spinal cord injury (SCI). Methods: All …

ABSTRACT Purpose: We used Anakinra to inhibit the expression of IL-1β based on the
model of spinal cord injury in the rat stomach and explored whether it had a certain …

ABSTRACT BACKGROUND: The aim of this study was to evaluate the therapeutic efficiency
of Anakinra, an IL-1β antagonist with anti-inflammatory effects, in an experimental model of …

Spinal cord injury (SCI), mostly caused by sports injuries, falls, or traffic accidents, is a major
cause of disability. The aim of current work was to investigate the therapeutic effect of …

We assessed the effect of treatment with the interleukin-1 receptor antagonist protein (IRAP)
on morphological and functional recovery in a rat model of SCI. All sections were processed …

Objective In spinal cord injury (SCI), the primary mechanical damage leads to a
neuroinflammatory response and the secondary neuronal injury occurs in response to the …

Neuroprotective effect of Acute Interferon-Beta 1B Treatment after Spinal Cord Injury Page 1 O
rig inal In vestigations Turkish Neurosurgery 2013, Vol: 23, No: 1, 45-49 45 Received …

Introduction Oxidative stress and inflammatory responses are often the predominant
detrimental factors associated with spinal cord injury (SCI). This study investigates the …

Background Glial and fibrotic scars inhibit neural regeneration after spinal cord injury (SCI).
N-[3, 4-dimethoxycinnamoyl]-anthranilic acid (tranilast) inhibits transforming growth factor β …

Context/Objective: Following acute spinal cord injury (ASCI) in rabbits, subarachnoid space
injection of Danshen was performed to protect the neurological damage. In this study, we …