Beneficial effects of edaravone on the expression of serum matrix metalloproteinase-9 after cerebral hemorrhage

F Zhao, Z Liu - Neurosciences Journal, 2014 - nsj.org.sa
OBJECTIVE: To explore the effects of edaravone on the expression of matrix
metalloproteinase-9 (MMP-9) posterior to cerebral hemorrhage, and to analyze the …

Expression of matrix metalloproteinase MMP-9 in the plasma and hematoma fluid of intracerebral hemorrhage patients

CH Wu, FY Huang, KY Wang, SY Huang… - Zhonghua Yi Xue …, 2008 - europepmc.org
Objective To investigate the matrix metalloproteinase (MMP)-9 played in secondary brain
injury following intracerebral hemorrhage (ICH). Methods Hematoma fluid and peripheral …

Edaravone, a free radical scavenger, inhibits MMP-9–related brain hemorrhage in rats treated with tissue plasminogen activator

K Yagi, KT Kitazato, M Uno, Y Tada, T Kinouchi… - Stroke, 2009 - Am Heart Assoc
Background and Purpose—Intracerebral hemorrhage, induced by recombinant tissue
plasminogen activator (rtPA) in ischemic stroke, is attributable to the increased activity of …

A therapeutic target of cerebral hemorrhagic stroke: matrix metalloproteinase-9

B Dang, X Duan, Z Wang, W He, G Chen - Current drug targets, 2017 - ingentaconnect.com
Background: Cerebral hemorrhagic stroke, including intracerebral hemorrhage (ICH),
subarachnoid hemorrhage (SAH), and hemorrhagic transformation after cerebral infarction …

Relationship of plasma matrix metalloproteinase-9 and hematoma expansion in acute hypertensive cerebral hemorrhage

Q Yang, X Zhuang, F Peng, W Zheng - International Journal of …, 2016 - Taylor & Francis
In the present study, we aimed to investigate the relationship of plasma matrix
metalloproteinase-9 (MMP-9) and hematoma expansion (HE) in acute hypertensive cerebral …

Effects of minimally invasive procedures for removal of intracranial hematoma on matrix metalloproteinase expression and blood-brain barrier permeability in …

G Wu, L Wang, Z Hong, C Li, X Long… - Neurological …, 2011 - Taylor & Francis
Objective: To observe the effects of minimally invasive removal of intracerebral hematoma
on perihematomal matrix metalloproteinase (MMP)-9 expressions and permeability of blood …

Matrix metalloproteinase—9 concentration after spontaneous intracerebral hemorrhage

S Abilleira, J Montaner, CA Molina, J Monasterio… - Journal of …, 2003 - thejns.org
Object. Matrix metalloproteinases (MMPs) are overexpressed in the presence of some
neurological diseases in which blood—brain barrier disruption exists. The authors …

Matrix metalloproteinase-9: dual role and temporal profile in intracerebral hemorrhage

JJ Chang, BA Emanuel, WJ Mack, G Tsivgoulis… - Journal of Stroke and …, 2014 - Elsevier
Background Clinical outcome after intracerebral hemorrhage (ICH) remains poor. Recent
trials in ICH, focusing on hematoma reduction, have not yielded significant clinical …

Plasma metalloproteinase-9 concentration predicts hemorrhagic transformation in acute ischemic stroke

M Castellanos, R Leira, J Serena, JM Pumar… - Stroke, 2003 - Am Heart Assoc
Background and Purpose—Matrix metalloproteinase-9 (MMP-9) activity has been
associated with hemorrhagic transformation (HT) in experimental models of cerebral …

MMP-9 expression and activity is concurrent with endothelial cell apoptosis in the basilar artery after subarachnoid hemorrhaging in rats

Z Guo, L Xu, X Wang, X Sun - Neurological Sciences, 2015 - Springer
Subarachnoid hemorrhage refers to one kind of lethal stroke. While several studies have
shown the role of matrix metalloproteinase 9 in cerebral tissues and microvasculature after …