[CITATION][C] Free radical injury for in vivo induction of platelet aggregation. A model in microcirculatory studies of the brain

FM El-Sabban - Neurosciences Journal, 2008 - nsj.org.sa
Blood supply to tissues is very important, as it carries oxygen and nutrients needed for
normal biological processes in cells. Exchange between the blood and tissue takes place at …

Platelet-endothelial interaction within the cerebral microcirculation.

MA Said - 1994 - elibrary.ru
The role of platelet aggregation in the exacerbation of preexisting endothelial damage, and
the permeability changes associated with such damage were assessed in the cerebral …

Effects of combined parenchymal and vascular injury on platelet aggregation in pial arterioles of living mice: evidence for release of aggregate-inhibiting materials.

WI Rosenblum, F El-Sabban - Stroke, 1977 - Am Heart Assoc
Platelet aggregation was produced in pial arterioles by exposing them to appropriately
filtered light from a mercury lamp, following intravascular injection of sodium fluorescein. The …

Correlations between morphological changes in platelet aggregates and underlying endothelial damage in cerebral microcirculation of mice.

S Said, WI Rosenblum, JT Povlishock, GH Nelson - Stroke, 1993 - Am Heart Assoc
The aim of this study was to test the hypothesis that, once formed, platelet aggregates may
injure underlying cerebrovascular endothelium. Such injury could make the same site …

Platelet aggregation in the cerebral microcirculation: effect of aspirin and other agents.

WI Rosenblum, F El-Sabban - Circulation Research, 1977 - Am Heart Assoc
After a certain period of time filtered ultraviolet light produces platelet aggregation in
microvessels on the cerebral surface of the mouse, but only when sodium fluorescein is first …

Dimethyl sulfoxide (DMSO) and glycerol, hydroxyl radical scavengers, impair platelet aggregation within and eliminate the accompanying vasodilation of, injured …

WI Rosenblum, F El-Sabban - Stroke, 1982 - Am Heart Assoc
The hydroxyl radical scavengers dimethyl sulfoxide (DMSO) and glycerol were effective
inhibitors of platelet aggregation in an in vivo mouse model of pial arteriolar injury …

Cerebrovascular injuries induced by activation of platelets in vivo.

T Fujimoto, H Suzuki, K Tanoue, Y Fukushima… - Stroke, 1985 - Am Heart Assoc
Intravascular platelet aggregation induced by ADP injection into the carotid artery of rabbits
caused ipsilateral cerebrovascular injuries. We have observed the details of these in vivo …

An ultrastructural analysis of endothelial change paralleling platelet aggregation in a light/dye model of microvascular insult.

JT Povlishock, WI Rosenblum… - The American Journal …, 1983 - ncbi.nlm.nih.gov
Those microvascular endothelial events that parallel the evolution of platelet aggregation
were evaluated in a well-controlled animal model. Cat pial microvessels were observed …

Platelet aggregation induced in the hamster cheek pouch by a photochemical process with excited fluorescein isothiocyanate-dextran

KS Herrmann - Microvascular research, 1983 - Elsevier
Excitation of intravascular fluorescein isothiocyanate (FITC)-dextran by light induces platelet
aggregation in arterioles of the hamster cheek pouch. Time to aggregate appearance (TAA) …

Effect of intravascular platelet aggregation on blood recirculation following prolonged ischemia of the cat brain

V Hossmann, KA Hossmann, S Takagi - Journal of Neurology, 1980 - Springer
Reversible complete cerebro-circulatory arrest was produced in normothermic, anesthetized
cats for 1 h by clamping the innominate and subclavian arteries, followed by blood …