Low versus standard dose intravenous alteplase in the treatment of acute ischemic stroke in Egyptian patients

GM Salem, WM El-Sheik, BG El-Shanawany… - Neurosciences …, 2021 - nsj.org.sa
Objectives: To assess low dose altepase outcome and safety in comparison with a standard-
dose regimen for acute ischemic stroke treatment in Egyptian patients. Materials: An …

[HTML][HTML] Low-dose versus standard-dose intravenous alteplase in acute ischemic stroke

CS Anderson, T Robinson, RI Lindley… - … England Journal of …, 2016 - Mass Medical Soc
Background Thrombolytic therapy for acute ischemic stroke with a lower-than-standard dose
of intravenous alteplase may improve recovery along with a reduced risk of intracerebral …

Comparative analysis on low-and standard-dose regimes of alteplase thrombolytic therapy for acute ischemic stroke: efficacy and safety

G Zhao, T Huang, M Zheng, Y Cui, Y Liu, Z Cheng… - European …, 2018 - karger.com
Objective: This study analyzed the efficacy and safety of low-dose and standard-dose
alteplase intravenous thrombolytic therapy for acute ischemic stroke (AIS). Methods: Patients …

Safety and efficacy of intravenous low-dose alteplase in relative contraindication patients with acute ischemic stroke

T Ohta, K Okada, M Fukuda, N Masahira… - Journal of Stroke and …, 2018 - Elsevier
Object The purpose of this study was to investigate the safety and efficacy of intravenous low-
dose alteplase for acute ischemic stroke patients with relative contraindications. Methods …

[HTML][HTML] Low-dose versus standard-dose alteplase for intravenous thrombolysis in patients with acute ischemic stroke in Iran: Results from the safe implementation of …

E Sadeghi-Hokmabadi, A Ghoreishi… - Current Journal of …, 2021 - ncbi.nlm.nih.gov
Background: Rates of intracranial hemorrhage (ICH) after intravenous thrombolysis (IVT)
differ depending on ethnicity, one reason that few Eastern countries have approved a lower …

Alteplase compared with placebo within 3 to 4.5 hours for acute ischemic stroke

W Hacke, M Kaste, E Bluhmki, M Brozman… - NEW ENGLAND …, 2008 - iris.uniroma1.it
Background Intravenous thrombolysis with alteplase is the only approved treatment for acute
ischemic stroke, but its efficacy and safety when administered more than 3 hours after the …

Low-dose versus standard-dose alteplase in acute ischemic stroke in Asian stroke registries: an individual patient data pooling study

X Wang, J Li, TJ Moullaali, KJ Lee… - … Journal of Stroke, 2019 - journals.sagepub.com
Objective To investigate the comparative efficacy and safety of the low-dose versus standard-
dose alteplase using real-world acute stroke registry data from Asian countries. Methods …

The effectiveness of thrombolysis with intravenous alteplase for acute ischemic stroke in daily practice

M Dirks, LW Niessen… - … Journal of Stroke, 2012 - journals.sagepub.com
Background Thrombolysis with intravenous alteplase has been proven an effective
treatment for patients with acute ischemic stroke in randomized clinical trials. In daily …

Low-dose alteplase for the management of acute ischemic stroke in South Asians: A systematic review on cost, efficacy and safety

G Nepal, S Kharel, JK Yadav, SK Yadav… - Journal of Clinical …, 2022 - Elsevier
Abstract Introduction South Asia is responsible for more than 40% of the stroke burden and
stroke mortality in the developing world. South Asia, which is home to one-fourth of the …

Effects of alteplase in the treatment of acute ischemic stroke

J Yayan - International Journal of General Medicine, 2012 - Taylor & Francis
Background For the last 15 years, alteplase (recombinant tissue plasminogen activator) has
been used widely throughout the world for the treatment of acute ischemic stroke. Although …