[HTML][HTML] Tolerability and discontinuation rates in teriflunomide-treated patients: a real-world clinical experience

HA Alnajashi, FJ Alshamrani, MS Freedman - Neurosciences Journal, 2018 - nsj.org.sa
Objectives: To assess the real-world tolerability of teriflunomide in multiple sclerosis (MS)
patients from a large Canadian MS Centre of Care to determine whether previously treated …

[HTML][HTML] Teriflunomide real-world evidence: global differences in the phase 4 Teri-PRO study

PK Coyle, B Khatri, KR Edwards… - Multiple Sclerosis and …, 2019 - Elsevier
Background The demographics and management of patients with multiple sclerosis (MS)
differ across geographical regions, but it is unclear whether/how these differences affect …

Real world experience with teriflunomide in multiple sclerosis: the TER-Italy study

S Bucello, P Annovazzi, P Ragonese, M Altieri… - Journal of …, 2021 - Springer
Objective To identify baseline factors associated with disease activity in patients with
relapsing–remitting multiple sclerosis (RRMS) under teriflunomide treatment. Methods This …

12-Year Clinical Efficacy and Safety Data for Teriflunomide: Results from a Phase 2 Extension Study (P7. 223)

M Kremenchutzky, M Freedman, A Bar-Or, D Dukovic… - Neurology, 2015 - AAN Enterprises
OBJECTIVE: To report long-term efficacy and safety data from patients treated with
teriflunomide for≤ 12 years. BACKGROUND: Teriflunomide is a once-daily oral …

Efficacy and safety of teriflunomide in multiple sclerosis across age groups: analysis from pooled pivotal and real-world studies

J Oh, S Vukusic, K Tiel-Wilck… - Journal of Central …, 2021 - journals.sagepub.com
Background: Evidence suggests that efficacy and safety of disease-modifying treatments for
multiple sclerosis may differ with age. We evaluate efficacy and safety of teriflunomide …

Teriflunomide in relapsing-remitting multiple sclerosis: outcomes by age and pre-treatment status

BA Kallmann, S Ries, JS Kullmann… - Therapeutic …, 2021 - journals.sagepub.com
Background and aims: To investigate effectiveness and safety of teriflunomide (14 mg once
daily) in association with age and pre-treatment in unselected MS patients. Methods …

[HTML][HTML] Pooled safety and tolerability data from four placebo-controlled teriflunomide studies and extensions

G Comi, MS Freedman, L Kappos, TP Olsson… - Multiple sclerosis and …, 2016 - Elsevier
Background Teriflunomide, a once-daily oral immunomodulator for the treatment of
relapsing-remitting multiple sclerosis, has demonstrated consistent efficacy on clinical and …

Long-term safety and efficacy of teriflunomide in patients with relapsing multiple sclerosis: results from the TOWER extension study

AE Miller, TP Olsson, JS Wolinsky, G Comi… - Multiple sclerosis and …, 2020 - Elsevier
Background In the phase 3 TOWER core study (NCT00751881), the efficacy and safety of
teriflunomide compared with placebo were demonstrated in patients with relapsing forms of …

Teriflunomide for multiple sclerosis in real‐world setting

ML Elkjær, T Molnar, Z Illes - Acta Neurologica Scandinavica, 2017 - Wiley Online Library
Objectives Teriflunomide 14 mg is a once‐daily oral disease‐modifying treatment for
relapsing‐remitting multiple sclerosis. We examined adverse event (AE) profile and efficacy …

[HTML][HTML] Real-world outcomes for a complete nationwide cohort of more than 3200 teriflunomide-treated multiple sclerosis patients in The Danish Multiple Sclerosis …

V Papp, MD Buron, V Siersma, PV Rasmussen, Z Illes… - PLoS …, 2021 - journals.plos.org
Objective Teriflunomide is a once-daily, oral disease-modifying therapy (DMT) for relapsing
forms of multiple sclerosis (MS). We studied clinical outcomes in a real-world setting …