Clipping versus coiling for ruptured intracranial aneurysms after the international subarachnoid aneurysm trial. United Kingdom experience

MS Taha, UJ Patel - Neurosciences Journal, 2009 - nsj.org.sa
The International Subarachnoid Aneurysm Trial (ISAT) was designed as the first multi-
central international prospective randomized trial aiming to compare the safety and efficacy …

International Subarachnoid Aneurysm Trial (ISAT) of neurosurgical clipping versus endovascular coiling in 2143 patients with ruptured intracranial aneurysms: a …

A Molyneux - The Lancet, 2002 - thelancet.com
Background Endovascular detachable coil treatment is being increasingly used as an
alternative to craniotomy and clipping for some ruptured intracranial aneurysms, although …

[HTML][HTML] International subarachnoid aneurysm trial–ISAT part II: study protocol for a randomized controlled trial

TE Darsaut, AS Jack, RS Kerr, J Raymond - Trials, 2013 - Springer
Abstract Background The International Subarachnoid Aneurysm Trial (ISAT) demonstrated
improved one-year clinical outcomes for patients with ruptured intracranial aneurysms …

[HTML][HTML] The durability of endovascular coiling versus neurosurgical clipping of ruptured cerebral aneurysms: 18 year follow-up of the UK cohort of the International …

AJ Molyneux, J Birks, A Clarke, M Sneade, RSC Kerr - The Lancet, 2015 - thelancet.com
Background Previous analyses of the International Subarachnoid Aneurysm Trial (ISAT)
cohort have reported on the risks of recurrent subarachnoid haemorrhage and death or …

International subarachnoid aneurysm trial 2009: endovascular coiling of ruptured intracranial aneurysms has no significant advantage over neurosurgical clipping

NA Bakker, JDM Metzemaekers, RJM Groen… - …, 2010 - journals.lww.com
In the May 2009 issue of The Lancet Neurology, the 5-year follow-up results of the
International Subarachnoid Aneurysm Trial (ISAT) were published. The authors concluded …

The International Subarachnoid Aneurysm Trial II: comparison of clipping vs coiling: key questions. Are the results of the study generalizable? Should clipping be done …

JI Ausman - Surgical neurology, 2008 - europepmc.org
This is a comment on" Could late rebleeding overturn the superiority of cranial aneurysm coil
embolization over clip ligation seen in the International Subarachnoid Aneurysm Trial?" J …

Treatment of ruptured intracranial aneurysms: looking to the past to register the future

JF Fraser, H Riina, N Mitra, YP Gobin, AS Simon… - …, 2006 - journals.lww.com
OBJECTIVE The outcomes reported in the International Subarachnoid Aneurysm Trial
(ISAT), a multicenter, prospective, randomized trial to directly compare surgical clipping with …

[HTML][HTML] Risk of recurrent subarachnoid haemorrhage, death, or dependence and standardised mortality ratios after clipping or coiling of an intracranial aneurysm in …

AJ Molyneux, RSC Kerr, J Birks, N Ramzi… - The Lancet …, 2009 - thelancet.com
Background Our aim was to assess the long-term risks of death, disability, and rebleeding in
patients randomly assigned to clipping or endovascular coiling after rupture of an …

Ruptured aneurysms and the International Subarachnoid Aneurysm Trial (ISAT): What is known and what remains to be questioned

J Raymond, M Kotowski, TE Darsaut, AJ Molyneux… - Neurochirurgie, 2012 - Elsevier
BACKGROUND AND PURPOSE: The International Subarachnoid Aneurysm Trial (ISAT)
was a major study comparing clipping and coiling of ruptured intracranial aneurysms. The …

International subarachnoid trial in the long run: critical evaluation of the long-term follow-up data from the ISAT trial of clipping vs coiling for ruptured intracranial …

DMS Raper, R Allan - Neurosurgery, 2010 - journals.lww.com
Abstract The International Subarachnoid Trial (ISAT), the largest prospective randomized
study into endovascular and neurosurgical treatment of ruptured intracranial aneurysms …