Holoprosencephaly (HPE) is a defect of embryonic forebrain resulting from failure of growth
and segmentation of the anterior end of the neural tube. It has been classified into 4 types …

Holoprosencephaly is a rare congenital brain malformation resulting from failure of
diverticulation and cleavage of primitive prosencephalon which occurs at 4-8th week of …

Background: Holoprosencephaly is a developmental defect of the embryonic forebrain, or
prosencephalon that is commonly associated with midfacial defects. The defect results from …

Holoprosencephaly is a complex developmental abnormality of the brain arising from the
failure of cleavage of the prosencephalon. The condition termed “holoprosencephaly” …

Holoprosencephaly is a rare spectrum of congenital malformation associated with midline
facial defects and absence of olfactory tract. Sequence occurs at 4 th to 8 th week of …

Background Holoprosencephaly is a rare spectrum of cephalic disorders resulting from a
failure or incomplete division of the embryonic forebrain into distinct cerebral hemispheres. It …

Holoprosencephaly is a rare and a complex congenital brain malformation resulting from
defective cleavage of the prosencephalon that occurs at 4-8th week of gestation and is …

Background The term holoprosencephaly was proposed by DeMyer and Zeman. It is a
developmental defect of the embryonic forebrain with heterogeneous etiology including …

Holoprosencephaly (HPE) is a rare congenital brain malformation associated with multiple
midline facial defects. This anomaly is resulted from the failure of diverticulation and …

Holoprosencephaly (HPE) is a birth defect that occurs during the first weeks of pregnancy
and as a result the prosencephalon does not clearly divide in diencephalon, two halves of …