OBJECTIVE: To determine how benzodiazepine (BZD) sensitivity testing might be utilized to
choose potentially useful antiepileptic drugs. METHODS: A retrospective audit of BZD …

The use of benzodiazepine sensitivity testing in the management of 40 children with
intractable seizure disorders was studied. The aetiology and clinical syndromes varied …

All benzodiazepine drugs (BZDs) may cause an increase in low-voltage beta activity in
human beings, but the mechanism and significance of this effect remains unknown.'The …

Abstract Objectives: To measure GABA A benzodiazepine receptor sensitivity in patients
taking benzodiazepines and compare with matched controls. Methods: Seven patients who …

Electrophysiological data suggest that an abnormal oscillatory pattern of discharge in
cortical and thalamic neurons may be the major mechanism underlying primary generalised …

The role of benzodiazepine (BZD)‐γ‐aminobutyric acid,(GABA) receptors in the
pathogenesis of absence seizures is uncertain. In this study, we examined the effect of …

We developed a model to predict the outcome of treatment with carbamazepine in children
with newly diagnosed focal epilepsy of presumed temporal lobe origin, using data available …

Benzodiazepines have been used in the treatment of epilepsy since the early 1970s. The
use of benzodiazepines in chronic epilepsy treatment has been limited by concerns for …

Fetal mouse cerebral cortex in culture was exposed chronically to diazepam, and
benzodiazepine (BDZ) receptor activity was assayed on the intact cell. Results have …

Impaired cortical inhibition may be involved in epileptogenic mechanisms. In a positron‐
emission tomography (PET) study, we demonstrated a reduction of the cortical …