A review of the gastrointestinal, olfactory, and skin abnormalities in patients with Parkinson's disease

MA Almikhlafi - Neurosciences Journal, 2024 - nsj.org.sa
Parkinson's disease (PD) is a complex neurodegenerative motor disorder caused by the
loss of dopaminergic neurons in the substantia nigra pars compacta. The substantia nigra is …

Premotor, nonmotor and motor symptoms of Parkinson's disease: a new clinical state of the art

ABRL Silva, RWG de Oliveira, GP Diógenes… - Ageing Research …, 2023 - Elsevier
Parkinson's Disease (PD) is a neurodegenerative disorder that affects dopaminergic
neurons in the mesencephalic substantia nigra, causing a progressive clinical course …

[HTML][HTML] Intestinal inflammation and Parkinson's disease

Y Li, Y Chen, L Jiang, J Zhang, X Tong, D Chen… - Aging and …, 2021 - ncbi.nlm.nih.gov
Parkinson's disease (PD) is the second most common neurodegenerative disease which
significantly influences the life quality of patients. The protein α-synuclein plays an important …

The gut and nonmotor symptoms in Parkinson's disease

L Klingelhoefer, H Reichmann - International review of neurobiology, 2017 - Elsevier
Gastrointestinal (GI) symptoms are one of the most common nonmotor symptoms (NMS) in
patients with Parkinson's disease (PD) involving the whole GI tract (GIT) and being evident …

[HTML][HTML] Non-motor symptoms of Parkinson's disease: the patient's perspective

KC Breen, G Drutyte - Journal of neural transmission, 2013 - Springer
Parkinson's disease (PD) can be manifested in many different ways. Although motor
dysfunction represents the best characterised of the symptoms, the non-motor symptoms …

[HTML][HTML] Gastrointestinal symptoms of Parkinson's disease: A systematic review from pathogenesis to management

XY Cheng, CJ Mao, YL Wang, CF Liu - Advanced Neurology, 2022 - accscience.com
The identification of Parkinson's disease (PD) is mainly dependent on motor symptoms,
while the non-motor symptoms exist even decades ahead of the PD diagnosis. According to …

Gastrointestinal manifestations in Parkinson's disease: prevalence and occurrence before motor symptoms

MG Cersosimo, GB Raina, C Pecci, A Pellene… - Journal of …, 2013 - Springer
To assess the prevalence of gastrointestinal symptoms (GIS) in Parkinson's disease (PD)
compared to control subjects and their timing of appearance in relationship to the onset of …

[HTML][HTML] Gut microenvironmental changes as a potential trigger in Parkinson's disease through the gut–brain axis

SJ Chen, CH Lin - Journal of Biomedical Science, 2022 - Springer
Parkinson's disease (PD) is the second most common neurodegenerative disease attributed
to the synergistic effects of genetic risk and environmental stimuli. Although PD is …

[HTML][HTML] Many faces of Parkinson's disease: non-motor symptoms of Parkinson's disease

HM Lee, SB Koh - Journal of movement disorders, 2015 - ncbi.nlm.nih.gov
Parkinson's disease (PD) is a multi-systemic disorder that is characterized by a combination
of motor and non-motor symptoms (NMS). The dopaminergic neurodegeneration of PD is …

[HTML][HTML] What is the evidence that Parkinson's disease is a prion disorder, which originates in the gut?

M Kujawska, J Jodynis-Liebert - International Journal of Molecular …, 2018 - mdpi.com
Parkinson's disease (PD) is a neurodegenerative disorder resulting from degeneration of
dopaminergic neurons in the substantia nigra pars compacta (SNpc). PD is characterized by …