OBJECTIVE: To investigate if the addition of dexmedetomidine to meperidine in a patient-
controlled analgesia (PCA) device would reduce postoperative meperidine consumption …

Hypothesis Intravenous patient-controlled analgesia (IV PCA) meperidine hydrochloride can
be used with a reasonable margin of safety. Design A retrospective review was performed of …

We examined the relationship between serum concentrations of meperidine hydrochloride
and analgesic response in postsurgical patients allowed to use patient-controlled analgesia …

SummaryBackground and objective: This prospective, randomized, double-blind, controlled
study was designed to test the effect of pre-anaesthetic administration of dexmedetomidine …

BACKGROUND: Meperidine continues to be widely used, especially as a postoperative
analgesic agent, despite numerous pain management guidelines have recommended …

Purpose We hypothesized that a high dose of dexmedetomidine (1 μg/kg/h) could reduce
postoperative analgesic requirements of patients. Methods This was a prospective …

Background Perioperative use of dexmedetomidine is associated with reduction in
postoperative analgesic requirements. This study examined whether dexmedetomidine …

Purpose To determine the effects of the addition of a background infusion to patient-
controlled epidural analgesia (PCEA) using mependine for analgesia after Caesarean …

Background: This study was investigated the effects of dexmedetomidine in combination
with fentanyl-based intravenous patient-controlled analgesia (IV-PCA) on pain attenuation in …

Background: Meperidine has been shown to exhibit a sensory block in peripheral nerves.
However, its motor blockade ability is controversial. The aim of this study was to investigate …