OBJECTIVE: To evaluate the effect of leucine and genistein on the dopaminergic system in a
rat model of schizophrenia. METHODS: Behavioral effects of leucine and genistein on …

Schizophrenia (SZ) is categorized as neuropsychiatric disorder with reduced lifespan and
significant impairments in social and vocational functioning. One of the best proposed …

Haloperidol is a high potency typical neuroleptic used in the treatment of schizophrenia.
Administration of haloperidol produces muscles related side effects commonly known as …

Schizophrenia is one of the most disabling mental disorders that affects up to 1% of the
population worldwide. Although the causes of this disorder remain unknown, it has been …

A decrease in the levels of antioxidant arsenals exacerbate generation of reactive
oxygen/nitrogen species, leading to neurochemical dysfunction, with significant impact on …

A large body of experimental evidence supports a role for oxidative stress as a mediator of
nerve cell death in Parkinson's disease (PD). Phytoestrogens such as genistein have been …

Objective: Schizophrenia is a devastating disorder with its positive (hallucination and
delusion), negative (such as social withdrawal, anhedonia), and cognitive (learning and …

Objective: The objective of our study was to investigate the effects of chronic haloperidol
administration on glutamate dehydrogenase activity and GABA level. Methods: We used ex …

Objective: Acetylcholinesterase inhibitors are the focus of interest in the management of
schizophrenia. We aimed to investigate the effects of acute galangin administration, a …

Background: Sodium Benzoate (SB) significantly improved positive, negative, and cognitive
symptoms as add on treatment in schizophrenia. Olanzapine (Ola), the most effective …