Stroke is the third leading cause of death and a major cause of disability worldwide. Most
cases of ischemic stroke are attributable to hypertension and other risk factors, but in over …

Stroke or" brain attack" is a complex disease caused by a combination of multiple risk
factors. It has major social and economic consequences. Various epidemiological studies in …

The genetics of cerebrovascular disease is an area of increasing interest and advances.
During the past year there have been a number of significant discoveries in the area that …

We introduced our first edition of this book with the statement that 'our understanding of the
genetics of common diseases has come a long way in recent years'. That statement is as …

Background: A substantial portion of stroke risk remains unexplained, and a contribution
from genetic factors is supported by recent findings. In most cases, genetic risk factors …

Publisher Summary Stroke is a complex genetic trait, rather than a simple monogenic
disorder. This chapter introduces the approaches to current stroke genetic research. In …

Unravelling the Genetics of Ischaemic Stroke | PLOS Medicine Skip to main content
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Stroke is the second leading cause of death and the most common cause of disability in the
world. Its incidence is rising with increasing life expectancy. To relieve the heavy burden of …

Ischemic stroke has long been thought to have a genetic component that is independent of
conventional vascular risk factors. It has been estimated that over one half of stroke risk is …

Ischemic stroke is thought to have a polygenic basis, but identification of stroke susceptibility
genes and quantification of associated risks have been hampered by conflicting results from …