Association of apolipoprotein E epsilon 4 allele with sporadic late onset Alzheimer's disease. A meta-analysis

S Sadigh-Eteghad, M Talebi, M Farhoudi - Neurosciences Journal, 2012 - nsj.org.sa
OBJECTIVE: To obtain a better insight into the effect of the epsilon (e) 4 allele of the
apolipoprotein E gene (APOE) on the risk of late onset Alzheimer's disease (LOAD), and …

Association between apolipoprotein E gene polymorphism and Alzheimer's disease in an Iranian population: A meta-analysis

M Abyadeh, K Djafarian, F Heydarinejad… - Journal of Molecular …, 2019 - Springer
The development of Alzheimer's disease (AD) has been strongly linked to the apolipoprotein
E (APOE) polymorphism. A number studies have reported that the APOE ε4 allele is a …

Apolipoprotein E ε4 prevalence in Alzheimer's disease patients varies across global populations: a systematic literature review and meta-analysis

S Crean, A Ward, CJ Mercaldi, JM Collins… - Dementia and geriatric …, 2011 - karger.com
Background: The Ε4 allele of apolipoprotein E (APOE) is associated with Alzheimer's
disease (AD). However, attributable risk due to APOE4 varies by region and by …

Association between apolipoprotein E polymorphism and Alzheimer disease in Tehran, Iran

AV Raygani, M Zahrai, AV Raygani, M Doosti… - Neuroscience …, 2005 - Elsevier
Epsilon 4 allele of apolipoprotein E (APOE-ɛ4) is a major risk factor for Alzheimer's disease
(AD). The association of APOE allele frequencies with AD remains unknown in developing …

[HTML][HTML] Age and the association between apolipoprotein E genotype and Alzheimer disease: A cerebrospinal fluid biomarker–based case–control study

H Saddiki, A Fayosse, E Cognat, S Sabia… - PLoS …, 2020 - journals.plos.org
Background The ε4 allele of apolipoprotein E (APOE) gene and increasing age are two of
the most important known risk factors for developing Alzheimer disease (AD). The diagnosis …

High APOE epsilon 4 allele frequencies associated with Alzheimer disease in a Tunisian population

AA Rassas, H Mrabet Khiari, S Hadj Fredj… - Neurological …, 2012 - Springer
The goal of the study was to examine the Apolipoprotein E (APOE) genotypes in a Tunisian
sample of patients with Alzheimer disease (AD) and normal controls, and to compare the …

[HTML][HTML] APOE ε4 lowers age at onset and is a high risk factor for Alzheimer's disease; A case control study from central Norway

SB Sando, S Melquist, A Cannon, ML Hutton… - BMC neurology, 2008 - Springer
Background The objective of this study was to analyze factors influencing the risk and timing
of Alzheimer's disease (AD) in central Norway. The APOE ε4 allele is the only consistently …

Apolipoprotein E ε4 allele is unrelated to cognitive or functional decline in Alzheimer's disease: retrospective and prospective analysis

T Kleiman, K Zdanys, B Black, T Rightmer… - Dementia and geriatric …, 2006 - karger.com
Abstract Objective: The apolipoprotein E (ApoE) Ε4 allele is a well-documented genetic risk
factor for Alzheimer's disease (AD). Its role, if any, in the progression of cognitive and …

Apolipoprotein E ε4 allele frequency and age at onset of Alzheimer's disease

Y Davidson, L Gibbons, A Pritchard… - Dementia and geriatric …, 2006 - karger.com
The age distribution of the Ε4 allelic form of the apolipoprotein E gene (APOE) was
investigated in 630 patients with Alzheimer's disease (AD) with onset age ranging from 35 to …

Prevalence of apolipoprotein E4 genotype and homozygotes (APOE e4/4) among patients diagnosed with Alzheimer's disease: a systematic review and meta-analysis

A Ward, S Crean, CJ Mercaldi, JM Collins, D Boyd… - …, 2012 - karger.com
Background: Population allele frequencies of apolipoprotein E (APOE) vary by geographic
region. The purpose of this study is to summarize and evaluate published estimates for the …