Objective: To evaluate the potential therapeutic value of telmisartan (TMT) against diabetic
neuropathy (DN) and associated pain in Wistar rats. Methods: Peripheral DN was induced …

The present study was designed to investigate the potential of telmisartan, an angiotensin
AT1 receptor, in chronic constriction injury-induced neuropathic pain in rats. Four loose …

Objective Angiotensin (ANG) II type 1 receptor (AT1R) blockers have neuroprotective effects
against neuronal lesions. The present study examines whether the AT1R blocker …

Development of tolerance, inadequate relief, and potential toxicity of classical
antinociceptives warrant the investigation of the newer agents to relieve diabetic …

Introduction Diabetes-induced neuropathic pain is recognized as one of the most difficult
type of pain to treat and conventional analgesics are well known to be partially effective or …

Objectives: Neuropathic pain reduces the life qualities of patients with Diabetes mellitus.
Clinical guidelines recommend relief in diabetic neuropathic pain through the use of some …

Diabetes mellitus is a serious debilitating epidemic affecting all social strata in developing
as well as developed countries. Diabetic neuropathy is most common of secondary …

Despite the large arsenal of analgesic medications, neuropathic pain (NP) management is
not solved yet. Angiotensin II receptor type 1 (AT1) has been identified as a potential target …

Diabetic neuropathy is recognized as one of the most common complications of chronic
diabetes, but its pathophysiological mechanism is complex and yet to be completely …

Diabetic peripheral neuropathic pain (DPNP) is a common and intractable complication of
diabetes. Conventional therapies are always not ideal; development of novel drugs is still …