[CITATION][C] Neonatal dexamethasone exposure in rats resulted in hippocampal learning and memory defects with decreased convulsion threshold later in adult life
SN Qaheri, AB Ali, AA Alalwaan, FA Ahmed… - Neurosciences …, 2013 - nsj.org.sa
Premature infants may be born with lung disease and difficulty in breathing. Dexamethasone
(DEX) is used widely for prevention and treatment of such cases. A previous study showed …
(DEX) is used widely for prevention and treatment of such cases. A previous study showed …
Effects of neonatal dexamethasone treatment on hippocampal synaptic function
HJ Lin, CC Huang, KS Hsu - … of Neurology: Official Journal of the …, 2006 - Wiley Online Library
Objective Synthetic glucocorticoid dexamethasone (DEX) is frequently used as a therapeutic
agent to lessen the morbidity of chronic lung disease in premature infants. Surprisingly, little …
agent to lessen the morbidity of chronic lung disease in premature infants. Surprisingly, little …
Neonatal dexamethasone on day 7 in rats causes behavioral alterations reflective of hippocampal, but not cerebellar, deficits
SA Ferguson, MG Paule, RR Holson - Neurotoxicology and Teratology, 2001 - Elsevier
Developmental glucocorticoid treatment in rats has been shown to cause body and brain
weight decrements concurrent with behavioral alterations. Here, Sprague–Dawley rats were …
weight decrements concurrent with behavioral alterations. Here, Sprague–Dawley rats were …
Dexamethasone prevents long-lasting learning impairment following neonatal hypoxic–ischemic brain insult in rats
T Ikeda, K Mishima, T Yoshikawa, K Iwasaki… - Behavioural brain …, 2002 - Elsevier
We examined for 18 weeks the effect of dexamethasone treatment on learning and memory
impairment produced by hypoxic–ischemic stress at postnatal day 7 in rat in addition to brain …
impairment produced by hypoxic–ischemic stress at postnatal day 7 in rat in addition to brain …
[HTML][HTML] The role of growth retardation in lasting effects of neonatal dexamethasone treatment on hippocampal synaptic function
YC Wang, CC Huang, KS Hsu - PLos one, 2010 - journals.plos.org
Background Dexamethasone (DEX), a synthetic glucocorticoid, is commonly used to prevent
or lessen the morbidity of chronic lung disease in preterm infants. However, evidence is now …
or lessen the morbidity of chronic lung disease in preterm infants. However, evidence is now …
Postnatal dexamethasone and long term learning and memory functions in developing rats: Effect of postnatal age and gender
N Machhor, T Balaji, TNK Raju - Life sciences, 2004 - Elsevier
In this study, we investigated the effect of dexamethasone on the long-term learning and
memory functions in developing rats. In Sprague-Dawley rat pups, we administered a daily …
memory functions in developing rats. In Sprague-Dawley rat pups, we administered a daily …
[HTML][HTML] A single postnatal dose of dexamethasone enhances memory of rat pups later in life
KJ Tsai, CI Sze, YC Lin, YJ Lin, TH Hsieh, CH Lin - PLoS One, 2016 - journals.plos.org
Postnatal dexamethasone (Dex) therapy is associated with adverse neurodevelopmental
outcomes, which might be related to its timing of administration. We used time-dated …
outcomes, which might be related to its timing of administration. We used time-dated …
Prenatal corticosteroid exposure affects hippocampal plasticity and reduces lifespan
CW Noorlander, GHA Visser… - Developmental …, 2008 - Wiley Online Library
Synthetic corticosteroids, such as dexamethasone, are frequently administered to pregnant
women at risk for preterm delivery. Endogenous corticosteroids are essential for normal …
women at risk for preterm delivery. Endogenous corticosteroids are essential for normal …
[HTML][HTML] Effects of neonatal corticosteroid treatment on hippocampal synaptic function
CC Huang, HR Lin, YC Liang, KS Hsu - Pediatric research, 2007 - nature.com
There is growing concern about long-term neurodevelopmental outcomes after neonatal
corticosteroid treatment for chronic lung disease (CLD). Here, we use a protocol with …
corticosteroid treatment for chronic lung disease (CLD). Here, we use a protocol with …
Neonatal glucocorticoid treatment increased depression-like behaviour in adult rats
MC Ko, YH Hung, PY Ho, YL Yang… - International Journal of …, 2014 - academic.oup.com
Synthetic glucocorticoid dexamethasone (DEX) is frequently used as a therapeutic agent to
lessen the morbidity of chronic lung disease in premature infants. Previous studies …
lessen the morbidity of chronic lung disease in premature infants. Previous studies …
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