Allicin can reduce neuronal death and ameliorate the spatial memory impairment in Alzheimers disease models

XH Li, CY Li, ZG Xiang, F Zhong, ZY Chen… - Neurosciences …, 2010 - nsj.org.sa
OBJECTIVE: To investigate the mechanisms and protective effects of allicin on learning and
memory in a mouse model of Alzheimer's disease (AD). METHODS: This study took place in …

Allicin ameliorates cognitive deficits ageing-induced learning and memory deficits through enhancing of Nrf2 antioxidant signaling pathways

XH Li, CY Li, JM Lu, RB Tian, J Wei - Neuroscience letters, 2012 - Elsevier
Numerous studies have demonstrated that learning and memory abilities in the course of
normal aging cognitive abilities tend to decline and Nrf2 expression appears to decline with …

Allicin ameliorates cognitive impairment in APP/PS1 mice via suppressing oxidative stress by blocking JNK signaling pathways

H Zhang, P Wang, Y Xue, L Liu, Z Li, Y Liu - Tissue and Cell, 2018 - Elsevier
In middle and old age, Alzheimer's disease (AD) is a progressive neurodegenerative
disorder of brain. As an increasingly aging population, AD represents a huge burden for the …

[HTML][HTML] Allantoin ameliorates amyloid β-peptide-induced memory impairment by regulating the PI3K/Akt/GSK-3β signaling pathway in rats

CY Tzeng, WS Lee, KF Liu, HK Tsou, CJ Chen… - Biomedicine & …, 2022 - Elsevier
Alzheimer's disease (AD) is a brain disease that causes problems in memory, thinking, and
behavior. Allantoin has been shown to have antioxidant, anti-inflammatory, and …

Protective effects of kinetin against aluminum chloride and D-galactose induced cognitive impairment and oxidative damage in mouse

Y Wei, D Liu, Y Zheng, H Li, C Hao, W Ouyang - Brain research bulletin, 2017 - Elsevier
Increasing evidence indicates that aluminum exposure and oxidative stress play crucial
roles in the initiation and development of Alzheimer's disease (AD). Aluminum chloride (AlCl …

Allicin ameliorates aluminium- and copper-induced cognitive dysfunction in Wistar rats: relevance to neuro-inflammation, neurotransmitters and Aβ(1–42) analysis

S Kaur, K Raj, YK Gupta, S Singh - JBIC Journal of Biological Inorganic …, 2021 - Springer
Alzheimer's disease (AD) is a multifactorial neurological disorder associated with
neuropathological and neurobehavioral changes, like cognition and memory loss …

Effects of allantoin on cognitive function and hippocampal neurogenesis

YJ Ahn, SJ Park, H Woo, HE Lee, HJ Kim… - Food and chemical …, 2014 - Elsevier
Allantoin is contained in Nelumbo nucifera (lotus) and a well-known cosmetic ingredient
reported to have anti-oxidative and anti-inflammatory activities. In the present study, we …

Allicin, an antioxidant and neuroprotective agent, ameliorates cognitive impairment

MS Nadeem, I Kazmi, I Ullah, K Muhammad, F Anwar - Antioxidants, 2021 - mdpi.com
Allicin (diallylthiosulfinate) is a defense molecule produced by cellular contents of garlic
(Allium sativum L.). On tissue damage, the non-proteinogenic amino acid alliin (S …

[HTML][HTML] Neuroprotective effects of ononin against the aluminium chloride-induced Alzheimer's disease in rats

X Chen, M Zhang, M Ahmed, KM Surapaneni… - Saudi journal of …, 2021 - Elsevier
Alzheimer's disease (AD) is a chronic neurodegenerative disease categorized by the
deficiency in the cognition and memory. Approximately 50 million peoples has the AD, which …

β-sitosterol Protects against Aluminium Chloride-mediated Neurotoxicity

S Yadav, P Aggarwal, F Khan, G Khodve… - Current Alzheimer …, 2023 - ingentaconnect.com
Objective: The objective of this study is to investigate the neuroprotective effects of β-
sitosterol using the AlCl3 model of Alzheimer's Disease. Methods: AlCl3 model was used to …